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c/t2dglp1·posted 3 months ago by u/wanjiru_osei

[Results] 51 weeks on 2.4mg, full numbers, ask me anything boring

Results Clean Column ×6 Receipts ×2

Quick one. Canada here.

CGM works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 17 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

5,373 up / 3,997 down57% upvoted52 commentsid ywbsiv24 Apr 2026

52 comments

28 in this archive, depth 5

best — the order this archive was captured in

u/fasting_insulin_fMOD214 points·3 months ago

Retitled to remove editorialising. Put the evidence in the body.

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u/marit_mwangi72 points·3 months ago

Strongly agree. A1c matters as much as weight.

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u/hassan_ostergaard23 points·3 months ago

Strongly agree.

Yes, exactly this, and it is the bit that took me 14 weeks to accept.

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u/not_my_main_nm0 points·3 months ago

Strongly agree.

Adding to this: metformin is doing more work than the comment implies.

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u/protein_first_pnutrition170 points·3 months ago·edited

Came off after 11 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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u/wanjiru_oseiOP110 points·3 months ago·edited

Maintenance for 4 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

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u/karim_ramos37 points·3 months ago

A1c, CGM, stacking with metformin

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u/sigrid_kaufmann51 points·3 months ago

Came off after 87 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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u/iman_castellanos162 points·3 months ago

Yeah, glycaemic control is the original use.

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u/amylin_amyamylin99 points·3 months ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/meal_prep_mira28 points·3 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/rasmus_kimani37 points·3 months ago

the 9 A1c trend is the answer

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u/fridge_door_no99 points·3 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/cormac_danquah49 points·3 months ago

Rodent data is rodent data.

Disagree on that part. 94.2% and 95.1% on the same vial is normal.

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u/thandi_solberg33 points·3 months ago

glycaemic control first, that is the original indication

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u/osman_ferrari94 points·3 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/kaia_cabrera78 points·3 months ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

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u/sock_puppet_spotter62 points·3 months ago·edited

post A1c with units and assay date

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u/niels_salinas68 points·3 months ago

Has anyone actually got this in writing, or is it forum lore at this point?

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u/wanjiru_osei21 points·3 months ago

glycaemic control first, that is the original indication

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u/wanjiru_oseiOP-28 points·3 months ago

Small correction: the trial was 24 weeks, not 36. Does not change your point but people will quote it.

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u/step_count_stan52 points·3 months ago

no medication-stopping advice, ever

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u/source_or_silence44 points·3 months ago

no medication-stopping advice, ever

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/cloudy_vial_carol35 points·3 months ago·edited

A1c, CGM, stacking with metformin

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u/wanjiru_osei28 points·3 months ago

A1c, CGM, stacking with metformin

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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[deleted]11 points·3 months ago

[deleted]

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u/slow_logbook_notes3012 points·3 months ago

CGM traces tell a story, numbers alone do not

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u/thandi_solberg45 points·3 months ago·edited

the ferritin change is the signal

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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