u/slow_logbook_notes30
Here for the tables, not the takes.
member · joined 24 Nov 2025
comment on amylin is not a GLP-1 and the co-agonism story is more interesting than the weight number in c/cagrilintide · 18 points · 2 days ago
REDEFINE readouts are phase 13 data
comment on [Trial Data] REDEFINE 1 — what cagri adds on top of sema in c/cagrilintide · 16 points · 2 days ago
Rodent or human data?
comment on [Trial Data] phase 2 biopsy endpoints, and what "resolution" means in c/survodutide · 27 points · 5 days ago
Not to be pedantic but survodutide and biopsy are being used interchangeably and they are not interchangeable in real life.
comment on [Lab] first independent cagrilintide purity number i have seen in c/cagrilintide · 13 points · 7 days ago
Rodent or human data?
comment on [Press Release] new phase 3 numbers, no publication yet, calm down in c/trialwatch · 15 points · 7 days ago
Strongly agree. Phase 2 is investigational, not conclusive.
comment on [Discussion] the weight conversation drowns out the glycaemic one in c/t2dglp1 · 12 points · 11 days ago
I am going to push back on this slightly.
comment on [Readout] REDEFINE 1 and what CagriSema actually adds over sema alone in c/trialwatch · 18 points · 13 days ago
Phase 2 TRIUMPH looked amazing.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
comment on [Question] A1c 5.6 but CGM says otherwise. which do i believe. in c/t2dglp1 · 26 points · 15 days ago
CGM traces tell a story, numbers alone do not
comment on [Stats] number needed to treat, or i am not interested in c/trialwatch · 106 points · 19 days ago
What was the dropout rate?
comment on [Results] 47 weeks, 36kg, and SURPASS was the hard part in c/trialwatch · 0 points · 25 days ago
off-label use data is different from approved-indication data
comment on stalled for 9 weeks at 12.5mg and I refuse to panic this time in c/survodutide · 4 points · 1 months ago
hepatic fat and MASH are the story
comment on the A1c thing finally clicked for me and I want to write it down in c/t2dglp1 · 34 points · 1 months ago
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
comment on genuine question about biopsy that I am slightly embarrassed to ask in c/survodutide · 1 points · 1 months ago
MASH claims need the trial and the biopsy endpoint
comment on 20 months in and A1c is still the thing I get wrong in c/t2dglp1 · 10 points · 2 months ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on glucagon — 17 things I got wrong before I got it right in c/survodutide · 1 points · 2 months ago
phase 16 data is interesting, phase 4 will be different
comment on tried CagriSema for 2 weeks. here is what happened. in c/cagrilintide · 12 points · 2 months ago
CagriSema is a fixed combo in trials, not user-mixed
comment on stalled for 20 weeks at 1.7mg and I refuse to panic this time in c/cagrilintide · 1 points · 2 months ago
This is correct. The co-agonism is real.
comment on [Results] 51 weeks on 2.4mg, full numbers, ask me anything boring in c/t2dglp1 · 12 points · 3 months ago
CGM traces tell a story, numbers alone do not
comment on reading cagrilintide threads from 2024 and half of it aged badly in c/cagrilintide · 1 points · 3 months ago
Strongly agree.
Adding to this: amylin is doing more work than the comment implies.
comment on reading cagrilintide threads from 2024 and half of it aged badly in c/cagrilintide · 1 points · 3 months ago
CagriSema is a fixed combo in trials, not user-mixed