metformin — 5 things I got wrong before I got it right
Quick one. Canada here.
CGM works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.
Specifics: the route I used took 20 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.
Happy to answer questions from anyone in the same jurisdiction.
best — the order this archive was captured in
Half-life is about 168 hours, so steady state lands around week 22–5. Practical consequence: what you feel in week 1 is not what that dose does.
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
Stalled for 18 weeks, changed nothing, and it started moving again on week 25.
the weight-loss conversation drowns out glycaemic control sometimes
insulin and sulfonylurea interactions are real hypo risk
glycaemic control first, that is the original indication
insulin and sulfonylurea interactions are real hypo risk
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
no medication-stopping advice, ever
Disagree but this is the good kind of wrong — it is specific enough to be checked.
no medication-stopping advice, ever
Adding to this: metformin is doing more work than the comment implies.
hypoglycaemia risk when stacked with metformin
Retitled to remove editorialising. Put the evidence in the body.
Yeah, glycaemic control is the original use.
This is correct. Hypo risk is real.
Ireland here. Waited 23 months on a list, gave up, went private, and the total cost was roughly what I expected.
post A1c with units and assay date
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
glycaemic control first, that is the original indication
I am going to push back on this slightly.
glycaemic control first, that is the original indication
the weight-loss conversation drowns out glycaemic control sometimes
Disagree but this is the good kind of wrong — it is specific enough to be checked.
What was the batch number and which service?
- 1This is correct. Hypo risk is real.10 comments in this branch · started by u/runa_grimaldi
- 2no medication-stopping advice, ever7 comments in this branch · started by u/gradient_goblin