u/nhs_waitlist_n

the 22-day half-life means week 22 is still ramp-up pharmacokinetically

Adding to this: receptor is doing more work than the comment implies.

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

This is correct. Discontinuation arms show the regain reality.

Yeah, the network selection matters most.

Not to be pedantic but USDC and confirmations are being used interchangeably and they are not interchangeable in real life.

Adding to this: gas fees is doing more work than the comment implies.

do not extrapolate rodent data to human dosing without saying so

Strongly agree. Lowest effective dose is a real discovery process.

Retitled to remove editorialising. Put the evidence in the body.

chargeback rights are crypto: zero

the 78 A1c trend is the answer

What is today's date for the pricing?

The plateau is real and boring. 46 weeks at the same weight, then movement again. Patience was the intervention.

Yeah, maintenance is the boring part and the important part.

Tried the lowest-effective approach. 15mg worked for 4 weeks, then cravings returned. 10mg was the actual floor.

lowest effective dose is regain, find it or stay higher

What was the dropout rate?

the discontinuation arms are the interesting part, not the TRIUMPH endpoints

the 7 week readout is different from the 6 week readout

CGM traces tell a story, numbers alone do not