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317

my eGFR moved and I cannot work out whether regain is why

Meta Cold Box ×2

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking maintenance against triglycerides for 13 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

451 up / 134 down77% upvoted29 commentsid orvxwc4 May 2025

29 comments

21 in this archive, depth 5

best — the order this archive was captured in

u/nhs_waitlist_nUK35 points·1 year ago

Strongly agree. Lowest effective dose is a real discovery process.

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u/bastian_aalto-20 points·1 year ago

Weight variance within what range?

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u/arne_ndiaye1 point·1 year ago

Yeah, maintenance is the boring part and the important part.

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u/rohan_cardoso1 point·1 year ago

regain is not a moral failing

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u/draw_up_dizzy1 point·1 year ago

the maintenance question changes at maintenance

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u/aleksi_eriksen10 points·1 year ago·edited

Strongly agree.

Adding to this: lowest effective dose is doing more work than the comment implies.

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u/neha_falk21 points·1 year ago

dose-stretching experiences welcome, dose-stretching instructions are not

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u/mod_cold_roommod · c/coldchain16 points·1 year ago

Disagree. What you are describing is consistent with regain, not with what you concluded.

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u/maintenance_mode_maxmaintenance5 points·1 year ago

Disagree.

Adding to this: goal weight is doing more work than the comment implies.

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[removed]4 points·1 year ago

[removed by moderator]

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u/paloma_stanescu4 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/noor_vermeulen3 points·1 year ago

regain after taper is expected, plan for it

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u/fridge_door_no1 point·1 year ago

Yeah, maintenance is the boring part and the important part.

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u/still_here_202618 points·1 year ago

lowest effective dose is dose stretching, find it or stay higher

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u/blunt_coldbox_notes11 points·1 year ago

lowest effective dose is dose stretching, find it or stay higher

Disagree on that part. 95.1% and 98.7% on the same vial is normal.

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u/osman_ferrari18 points·1 year ago

the 5mg dose works fine for 40 weeks of the month

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u/still_here_2026MOD12 points·1 year ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/priya_weiss3 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

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u/sanne_delgado2 points·1 year ago

the maintenance question changes at maintenance

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u/teodor_duarteOP1 point·1 year ago

food noise returns but not always immediately

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u/hassan_ostergaard1 point·1 year ago

the plateau is where the learning happens

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About c/maintenancephase

The part nobody posts about: what happens at goal weight. Finding a lowest effective dose, dose-interval stretching, regain risk data, muscle retention, the psychology of not having a number to chase, and staying on indefinitely versus tapering.

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c/maintenancephase rules
  1. State how long you have been at maintenance. "Maintenance" at week 30 is not maintenance.
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