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genuine question about SURMOUNT that I am slightly embarrassed to ask
Confession thread, sort of. I went from 7.5mg to 2.4mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 6 weeks…
u/draw_up_dizzy
Air bubble anxiety in an insulin syringe is not proportional to the risk.
newer member · joined 31 Mar 2025
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comment on [Paper] survodutide MASH data is the most interesting hepatic readout in the class in c/survodutide · 17 points · 2 days ago
MASH claims need the trial and the biopsy endpoint
comment on [Pricing] compounded tirz pricing in my state, six months of receipts in c/compounding · 7 points · 3 days ago
telehealth costs API source plus compounding markup, total varies
comment on [Pricing] compounded tirz pricing in my state, six months of receipts in c/compounding · 44 points · 3 days ago
What is the actual shortage list status right now?
comment on [Private Plan] special authorisation approved on the second try in c/glp1canada · 3 points · 4 days ago
province is the cross-province difference
comment on [Trial Data] phase 2 biopsy endpoints, and what "resolution" means in c/survodutide · 45 points · 5 days ago
Yeah, glucagon co-agonism is genuinely different.
comment on telehealth prescriber asked me three questions and approved me. that is not care. in c/compounding · 10 points · 6 days ago
no pharmacy referral codes, naming is fine, recruiting is not
comment on [Question] protein target in g/kg — of current weight or goal weight in c/glp1muscle · 8 points · 7 days ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on [Discussion] FFMI not weight, or you will celebrate losing muscle in c/glp1muscle · 7 points · 9 days ago
body-composition claims need a method
comment on intent-to-treat vs per-protocol explains half the arguments on this site in c/trialwatch · 13 points · 12 days ago
STEP 1 readout: 97.2% mean weight loss, absolute numbers matter. Spread around that mean is enormous.
comment on [Meta] how the ranking actually works, with the formula in c/meta · 1 points · 13 days ago
the ranking formula is moderation
comment on [Stats] number needed to treat, or i am not interested in c/trialwatch · 74 points · 19 days ago
Phase 2 TRIUMPH looked amazing. Phase 3 trials are harder. Do not anchor on phase 2 readouts.
comment on [Results] two years, weight stable within 3kg, dose at a quarter of peak in c/maintenancephase · 6 points · 21 days ago
Every time this gets posted it hits the front page and every time someone has to re-explain it.
Adding to this: long term is doing more work than the comment implies.
comment on am I the only one who found shortage list harder than the injections in c/compounding · 43 points · 23 days ago
503B compounding is different from 503A, different rules, different legality
comment on [Long Term] what my labs look like three years in in c/maintenancephase · 20 points · 28 days ago
food noise returns but not always immediately
comment on genuine question about SURMOUNT that I am slightly embarrassed to ask in c/trialwatch · 4 points · 28 days ago
phase 2 is not phase 3, smaller n and shorter trial
comment on genuine question about SURMOUNT that I am slightly embarrassed to ask in c/trialwatch · 7 points · 29 days ago
SELECT reported a SELECT hazard ratio but the absolute event rate is what changes clinical practice.
comment on genuine question about SURMOUNT that I am slightly embarrassed to ask in c/trialwatch · 10 points · 29 days ago
Disagree but this is the good kind of wrong — it is specific enough to be checked.
comment on [Discussion] API source is doing more work than we give it credit for in c/compounding · 2 points · 1 months ago
The 503A pharmacy I used lost their shortage list eligibility. Same day, compounding became illegal. Rules are real.
comment on stalled for 9 weeks at 12.5mg and I refuse to panic this time in c/survodutide · 49 points · 1 months ago
My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.