24 months in and lowest effective dose is still the thing I get wrong
Long-ish post, sorry. tl;dr at the bottom.
I have been tracking maintenance against eGFR for 3 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.
Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.
tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.
best — the order this archive was captured in
Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.
Inter-lab variance on this kind of assay is routinely 1–2 points.
Disagree on that part. 93.7% and 99.3% on the same vial is normal.
Slight fix: the number was 99.0, not 98.9. Decimal point, but a fairly consequential one.
the lowest dose you can stay on is not the lowest dose that works
Did you stretch the dose interval?
regain is not a moral failing
regain is not a moral failing
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
regain is not a moral failing
the 0.5mg dose works fine for 45 weeks of the month
How long at maintenance?
the plateau is where the learning happens
Did you stretch the dose interval?
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
state how long you have been at maintenance, week 18 is not maintenance
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food noise returns but not always immediately
The plateau is real and boring. 10 weeks at the same weight, then movement again. Patience was the intervention.
state how long you have been at maintenance, week 18 is not maintenance
Adding to this: goal weight is doing more work than the comment implies.
food noise returns but not always immediately
the 5mg dose works fine for 89 weeks of the month
Yeah, maintenance is the boring part and the important part.
How long at maintenance?
lowest effective dose is maintenance, find it or stay higher
The plateau is real and boring. 65 weeks at the same weight, then movement again. Patience was the intervention.
food noise returns but not always immediately
food noise returns but not always immediately
Disagree on that part. 96.8% and 96.2% on the same vial is normal.
This is correct. Weight variance is normal at maintenance.
lowest effective dose is lowest effective dose, find it or stay higher
- 1Did you stretch the dose interval?14 comments in this branch · started by u/erez_baptista
- 2How long at maintenance?7 comments in this branch · started by u/mod_cold_room