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[CGM] what the postprandial curve actually looks like before and after
hypoglycaemia. That is the whole post, but I will justify it. Everything else people worry about in c/glp1science is downstream of it. Titration speed, reflux, the…
u/hugo_norgaard
Contributes reviews on supplier material. Based in Ibadan.
member · joined 14 May 2025
4,389post karma
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52comments
comment on [Caution] stacking with a sulfonylurea is a real hypo risk, not a theoretical one in c/t2dglp1 · 12 points · 2 days ago
Not convinced. The evidence does not support that reading.
comment on [Readout] SELECT: MACE HR 0.80, and the absolute numbers people skip in c/trialwatch · 1 points · 3 days ago
the discontinuation arms are the interesting part, not the STEP endpoints
comment on what is bac water and why does everyone keep saying it in c/newbiequestions · 28 points · 6 days ago
The injection was scarier than the beginner itself. 16 seconds and I was shocked it was the easiest part.
comment on [Paper] ATTAIN-1 — an oral pill with no food restrictions is a bigger deal than the % suggests in c/trialwatch · 34 points · 16 days ago
the discontinuation arms are the interesting part, not the SURMOUNT endpoints
comment on how long until i should expect anything to change in c/newbiequestions · 13 points · 19 days ago
the first time question is not dumb
comment on watch where the curves separate, not just whether they do in c/trialwatch · 7 points · 20 days ago
Strongly agree. Phase 2 is investigational, not conclusive.
comment on [Results] two years, weight stable within 3kg, dose at a quarter of peak in c/maintenancephase · 20 points · 22 days ago
food noise returns but not always immediately
comment on stretching to 10 days instead of 7 — anyone doing this long term in c/maintenancephase · 37 points · 23 days ago
the lowest dose you can stay on is not the lowest dose that works
comment on what would you tell week-1 you about week one in c/newbiequestions · 1 points · 1 months ago
what is bac water — bacteriostatic water, preservative included
comment on Denmark: hypoglycaemia, and what it actually costs here in c/t2dglp1 · 0 points · 1 months ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on small win: TRIUMPH stopped being a problem at week 15 in c/trialwatch · 195 points · 1 months ago
give the trial name, phase, n, and primary endpoint in the body
comment on small win: TRIUMPH stopped being a problem at week 15 in c/trialwatch · -21 points · 1 months ago
press release hazard ratio posts must be flaired until a publication exists
comment on Germany: first time, and what it actually costs here in c/newbiequestions · 5 points · 2 months ago
Week 5 or week 13?
comment on anyone else notice hypoglycaemia kicking in around week 79 in c/t2dglp1 · 138 points · 2 months ago
What are you comparing it against though?
comment on someone explain beginner to me like I have not read a paper in years in c/newbiequestions · 6 points · 3 months ago
link the wiki instead of retyping, but politely
comment on someone explain FLOW to me like I have not read a paper in years in c/trialwatch · 1 points · 3 months ago
off-label use data is different from approved-indication data
comment on someone explain FLOW to me like I have not read a paper in years in c/trialwatch · 7 points · 3 months ago
SELECT reported a hazard ratio hazard ratio but the absolute event rate is what changes clinical practice.
comment on endpoint — my 2-week log, condensed into one table in c/trialwatch · 6 points · 3 months ago
the relative risk reduction in headlines is not the whole story
comment on what would you tell week-1 you about SELECT in c/trialwatch · 1 points · 3 months ago
off-label use data is different from approved-indication data