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c/trialwatch·posted 1 year ago by u/yannick_salinas

[Vendor] WXT order #23 — France, 9 days, no drama, receipts inside

Paper Clean Column ×3 Slow Clap ×2

Quick one. Canada here.

SURPASS works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US.

Specifics: the route I used took 14 weeks and cost roughly what I expected. The admin was worse than the cost. The thing that would have saved me the most time was knowing which document to ask for at the start.

Happy to answer questions from anyone in the same jurisdiction.

2,588 up / 520 down83% upvoted37 commentsid ynukmb3 Jan 2025

37 comments

15 in this archive, depth 4

best — the order this archive was captured in

u/hamza_weiss0 points·1 year ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/yannick_salinasOP1 point·1 year ago

STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix

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u/formulary_fighterappeals1 point·1 year ago

the 10 week readout is different from the 26 week readout

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u/hub_opssite staff199 points·1 year ago·edited

dropout handling matters, especially on GI-heavy populations

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u/forest_plot_fionastats126 points·1 year ago

Not convinced. The evidence does not support that reading.

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[deleted]54 points·1 year ago

[deleted]

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u/paper_trail_paulavetting153 points·1 year ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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u/rina_bergstrom223 points·1 year ago

Yeah, absolute numbers matter more than the press release.

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u/piotr_bruun150 points·1 year ago

STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix

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u/heart_rate_bump42 points·1 year ago

Strongly agree. Phase 2 is investigational, not conclusive.

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u/forest_plot_fionaMOD102 points·1 year ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/yannick_salinasOP40 points·1 year ago

Which trial and what was the primary endpoint?

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u/sanne_laurent74 points·1 year ago

SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.

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u/trialwatch_theotrial nerd-31 points·1 year ago

phase 2 is not phase 3, smaller n and shorter trial

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About c/trialwatch

Clinical trial reading group. New readouts, protocol amendments, endpoint definitions, dropout handling, and the difference between a press release and a publication. Absolute risk reduction and number-needed-to-treat are house dialect here.

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