u/yannick_salinas
Contributes reviews on supplier material. Based in Ilorin.
member · joined 16 Jul 2025
comment on [Paper] SURMOUNT-4 withdrawal arm, read the appendix not the abstract in c/trialwatch · 6 points · 3 days ago
Yeah, absolute numbers matter more than the press release.
comment on what is bac water and why does everyone keep saying it in c/newbiequestions · 56 points · 4 days ago
week two nothing happening — yes, that is normal
comment on [Trial Data] TRIUMPH timeline — what we actually know vs what gets repeated in c/retatrutide · 74 points · 6 days ago
This is correct. Triple agonism is genuinely different.
comment on [Question] why is reta purity testing so much more variable between labs in c/retatrutide · 19 points · 11 days ago
Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.
comment on [Readout] REDEFINE 1 and what CagriSema actually adds over sema alone in c/trialwatch · 112 points · 14 days ago
Strongly agree. Phase 2 is investigational, not conclusive.
comment on why does nobody talk about TRIUMPH in c/retatrutide · 26 points · 28 days ago
What was the dosing schedule in that arm?
comment on [Results] 12 weeks, 35kg, and FLOW was the hard part in c/trialwatch · 5 points · 1 months ago
Not to be pedantic but SELECT and endpoint are being used interchangeably and they are not interchangeable in real life.
comment on [Question] how do you actually verify amylin in c/cagrilintide · 144 points · 1 months ago
comment on [Meta] the endpoint rule is doing its job and people should stop complaining in c/trialwatch · 29 points · 1 months ago
Yeah, absolute numbers matter more than the press release.
comment on stalled for 5 weeks at 2.5mg and I refuse to panic this time in c/cagrilintide · 96 points · 1 months ago
This is correct. The co-agonism is real.
comment on [PSA] ATTAIN is not what most of this community thinks it is in c/orforglipron · 1 points · 1 months ago
the supply conversation changes if this approves
comment on glucagon vs TRIUMPH — genuinely asking which matters more in c/retatrutide · 5 points · 3 months ago
research use only, handling and analysis, not protocols
comment on glucagon vs TRIUMPH — genuinely asking which matters more in c/retatrutide · 44 points · 3 months ago
retatrutide is not approved anywhere for human use, posts must not read as instructions
comment on someone explain beginner to me like I have not read a paper in years in c/newbiequestions · 5 points · 3 months ago
the beginner question is not dumb
comment on [Results] 21 weeks on 1.0mg, full numbers, ask me anything boring in c/cagrilintide · 38 points · 3 months ago
not approved anywhere, keep posts descriptive, not instructional
comment on [Question] dose escalation — what am I missing here in c/retatrutide · 37 points · 4 months ago
comment on [Results] 62 weeks, 45kg, and FLOW was the hard part in c/trialwatch · 26 points · 4 months ago
the discontinuation arms are the interesting part, not the endpoint endpoints
comment on [Results] 62 weeks, 45kg, and FLOW was the hard part in c/trialwatch · 216 points · 4 months ago
press release hazard ratio posts must be flaired until a publication exists
comment on what changed for me between week 70 and week 18 in c/newbiequestions · 41 points · 4 months ago
no question too basic, read the wiki first, then ask anyway
comment on reading CagriSema threads from 2024 and half of it aged badly in c/cagrilintide · 13 points · 5 months ago
the mechanism is different, the side effect profile reflects it