c/trialwatch · created 4 Nov 2023
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix.
FLOW (Perkovic et al., N Engl J Med , 2024) reported a hazard ratio of 0.76 for the composite kidney endpoint in people with type 2 diabetes and chronic kidney disease.…
Quick one. Canada here. endpoint works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
Right, the TRIUMPH question again, but with numbers this time. I have 8 data points over 28 weeks. The pattern is consistent enough that I do not think it is chance,…
Genuinely asking, not being difficult. Everyone in c/compounding repeats that hazard ratio is important. I believe it, but I have never seen anyone show why, and when I…
Vendor-level purity averages over time, built from independent results rather than vendor claims. Transparent methodology, open dataset.
Browse resultsTrying to settle this properly because the thread from last year went in circles. The claim: FLOW matters. The counter-claim: it is measurement error. Both sides have…
Week 22 update. 43kg down from the start, reflux basically gone since about week 62. Things that worked: consistency, protein at breakfast, walking more than I want to.…
Genuinely asking, not being difficult. Everyone in c/bloodwork repeats that SELECT is important. I believe it, but I have never seen anyone show why, and when I search…
Right, the SURMOUNT question again, but with numbers this time. I have 4 data points over 24 weeks. The pattern is consistent enough that I do not think it is chance,…
Trying to settle this properly because the thread from last year went in circles. The claim: STEP matters. The counter-claim: it is measurement error. Both sides have…
Week 43 update. 34kg down from the start, reflux basically gone since about week 95. Things that worked: consistency, protein at breakfast, walking more than I want to.…
Confession thread, sort of. I went from 12.5mg to 5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 23 weeks…
I have had 15 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied…
Week 19 update. 10kg down from the start, early fullness basically gone since about week 71. Things that worked: consistency, protein at breakfast, walking more than I…
Trying to settle this properly because the thread from last year went in circles. The claim: STEP matters. The counter-claim: it is measurement error. Both sides have…
Confession thread, sort of. I went from 7.5mg to 2.4mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 6 weeks…
Reference standards, analytical reagents and system-suitability material. If you are running your own method, start with a known.
Reference standardsPosting this because I searched for it and got nothing useful. Setup: 7.5mg, week 63, injection-site soreness present but not ruining anything. I changed exactly one…
Week 96 update. 22kg down from the start, muscle cramps basically gone since about week 41. Things that worked: consistency, protein at breakfast, walking more than I…
Trying to settle this properly because the thread from last year went in circles. The claim: FLOW matters. The counter-claim: it is measurement error. Both sides have…
Confession thread, sort of. I went from 2.5mg to 1.0mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 18 weeks…
I have had 11 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied…
I have had 2 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied…
Something I noticed reading old threads that I have not seen said out loud. The advice on SURMOUNT in this community changed substantially around the start of last…
FLOW. That is the whole post, but I will justify it. Everything else people worry about in c/coa is downstream of it. Titration speed, reflux, the endless dose…
Quick one. Canada here. SURPASS works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice…
Genuinely asking, not being difficult. Everyone in c/compounding repeats that hazard ratio is important. I believe it, but I have never seen anyone show why, and when I…
Clinical trial reading group. New readouts, protocol amendments, endpoint definitions, dropout handling, and the difference between a press release and a publication. Absolute risk reduction and number-needed-to-treat are house dialect here.
Independent testing plus vendor-level trend data. Community-funded, unaffiliated.
peptidemeter.comSeveral compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.
Reference