u/piotr_bruun
Contributes reviews on supplier material. Based in Graz.
member · joined 12 Mar 2025
comment on [Explainer] why 1mL syringes cause overdoses and 0.3mL ones do not in c/reconstitution · 13 points · 4 days ago
never post a calculation as advice without stating the concentration
comment on [Explainer] why 1mL syringes cause overdoses and 0.3mL ones do not in c/reconstitution · 67 points · 5 days ago
dead space is real and the syringe matters
comment on do i need to keep it in the fridge before i mix it in c/newbiequestions · 8 points · 6 days ago
what is bac water — bacteriostatic water, preservative included
comment on cored the stopper on day 9. rotate your puncture site in c/reconstitution · 1 points · 6 days ago
This is correct. 2mL versus 10mL is the common mistake.
comment on [Stats] the placebo arm lost weight too. always ask by how much. in c/trialwatch · 16 points · 8 days ago
Yeah, absolute numbers matter more than the press release.
comment on what is a COA and how do i know if it is real in c/newbiequestions · 6 points · 9 days ago
What does the wiki say?
comment on sulphur burps: a taxonomy, a timeline, and my sincere apologies to my flatmate in c/sideeffects · 1 points · 15 days ago
Strongly agree. Describe your dose, your week number, and your titration speed or nobody can help.
comment on what does 0.25 mean, 0.25 of what in c/newbiequestions · 10 points · 15 days ago
link the wiki instead of retyping, but politely
Disagree on that part. 97.4% and 97.6% on the same vial is normal.
comment on [Paper] ATTAIN-1 — an oral pill with no food restrictions is a bigger deal than the % suggests in c/trialwatch · 0 points · 17 days ago
Slight fix: the number was 93.7, not 99.3. Decimal point, but a fairly consequential one.
comment on reconstituted at 1mL instead of 2mL and caught it before injecting. lucky. in c/reconstitution · 19 points · 17 days ago
What was the vial size and how much bac water?
comment on [Question] how long were you on before you tapered in c/tapering · 0 points · 17 days ago
tapering instructions are not welcome here
comment on small win: non-peptide stopped being a problem at week 16 in c/orforglipron · 10 points · 17 days ago
Stalled for 14 weeks, changed nothing, and it started moving again on week 11.
comment on genuine question about concentration that I am slightly embarrassed to ask in c/reconstitution · 72 points · 24 days ago
Not convinced. The evidence does not support that reading.
comment on [Results] 47 weeks, 36kg, and SURPASS was the hard part in c/trialwatch · 1 points · 24 days ago
give the trial name, phase, n, and primary endpoint in the body
comment on ACHIEVE — my 18-week log, condensed into one table in c/orforglipron · 52 points · 25 days ago
Second this question. I have wondered about small molecule for 18 months and never seen a straight answer.
comment on [Results] 12 weeks, 35kg, and FLOW was the hard part in c/trialwatch · 10 points · 1 months ago
Strongly agree. Phase 2 is investigational, not conclusive.
comment on silly question but which day of the week should i pick in c/newbiequestions · 92 points · 1 months ago
what is a COA — certificate of analysis, document from the lab
comment on what would you tell week-1 you about week one in c/newbiequestions · 19 points · 1 months ago
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
comment on week 71 check-in — 6kg down, constipation manageable, one thing confusing me in c/reconstitution · 8 points · 1 months ago
This is correct. 1mL versus 12mL is the common mistake.
comment on small molecule vs ATTAIN — genuinely asking which matters more in c/orforglipron · -11 points · 1 months ago
Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.