Something I noticed reading old threads that I have not seen said out loud. The advice on TRIUMPH in this community changed substantially around the start of last year,…
u/nhs_waitlist_n
UK. Two years of specialist-service waiting lists documented in painful detail.
long-standing contributor · UK · joined 19 Dec 2023
Overview — page 2 of 5
comment on the A1c thing finally clicked for me and I want to write it down in c/t2dglp1 · 135 points · 1 months ago
glycaemic control first, that is the original indication
comment on [Discussion] we are measuring regain at the wrong time and calling it noise in c/maintenancephase · 26 points · 1 months ago
state how long you have been at maintenance, week 15 is not maintenance
comment on someone explain pharmacy to me like I have not read a paper in years in c/glp1uk · 25 points · 2 months ago
Flair changed to match the content. Read the sidebar before posting next time and we are square.
comment on 18 months in and TRIUMPH is still the thing I get wrong in c/trialwatch · 0 points · 2 months ago
SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.
comment on 18 months in and TRIUMPH is still the thing I get wrong in c/trialwatch · 3 points · 2 months ago
SURMOUNT-4 discontinuation arm showed regain. That is the reality of a chronic disease treatment, not a failure.
comment on 18 months in and TRIUMPH is still the thing I get wrong in c/trialwatch · 1 points · 2 months ago
event rates are more informative than hazard ratios alone
comment on [Results] 87 weeks, 36kg, and endpoint was the hard part in c/trialwatch · 3 points · 2 months ago
SELECT reported a hazard ratio hazard ratio but the absolute event rate is what changes clinical practice.
comment on [Results] 86 weeks on 0.25mg, full numbers, ask me anything boring in c/glp1uk · 101 points · 3 months ago
private prescription routes vary by region
comment on the MHRA question that gets asked weekly, answered properly in c/glp1uk · -29 points · 3 months ago
Three years on this site and the questions have not changed at all.
Adding to this: NHS is doing more work than the comment implies.
comment on what would you tell week-1 you about SELECT in c/trialwatch · 1 points · 3 months ago
STEP 1 readout: 97.9% mean weight loss, absolute numbers matter. Spread around that mean is enormous.
comment on what would you tell week-1 you about SELECT in c/trialwatch · -34 points · 3 months ago
the relative risk reduction in headlines is not the whole story
comment on what would you tell week-1 you about SELECT in c/trialwatch · 3 points · 3 months ago
STEP 1 readout: 96.2% mean weight loss, absolute numbers matter. Spread around that mean is enormous.
Confession thread, sort of. I went from 1.7mg to 0.25mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 3 weeks…
comment on [Meta] the CGM rule is doing its job and people should stop complaining in c/t2dglp1 · 96 points · 3 months ago
comment on genuine question about pricing that I am slightly embarrassed to ask in c/glp1uk · 148 points · 4 months ago
price posts need the date — UK pricing moves monthly
comment on anyone else notice endpoint kicking in around week 19 in c/trialwatch · 147 points · 4 months ago
Phase 2 or phase 3?
comment on anyone else notice endpoint kicking in around week 19 in c/trialwatch · 433 points · 4 months ago
STEP, SURMOUNT, SURPASS, SELECT, FLOW, TRIUMPH — read the appendix
comment on dose stretching — 7 things I got wrong before I got it right in c/maintenancephase · 17 points · 4 months ago
That is net peptide content, not purity. Different number, different meaning.
comment on [Meta] the STEP rule is doing its job and people should stop complaining in c/trialwatch · 17 points · 5 months ago
Which trial and what was the primary endpoint?