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c/t2dglp1·posted 8 months ago by u/arne_nyberg

[Discussion] the T2D advice in here is 19 years out of date

Discussion Receipts ×3

I have had 12 orders now and I keep a table, so here is the honest summary rather than a vibe.

Material has been consistent. Communication has not. Shipping has varied by about 14 days on nominally the same lane, which matters more in summer than in February.

The independent number came back 98.4% against a claimed 98.6%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.

Batch number is in the comments. Ask if you want the method.

893 up / 216 down81% upvoted18 commentsid yc9fmy13 Nov 2025

18 comments

14 in this archive, depth 4

best — the order this archive was captured in

u/marta_weiss-29 points·8 months ago
this should be in the wiki
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u/farid_jansen1 point·8 months ago

CGM traces tell a story, numbers alone do not

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u/gustav_lindholm1 point·8 months ago

the 68 A1c trend is the answer

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u/joaquin_stanescu92 points·8 months ago
genuinely useful, thanks
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u/lucia_balogun46 points·8 months ago

You have restated the marketing copy. What is the actual substance here.

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u/marisol_moreau38 points·8 months ago

post A1c with units and assay date

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u/santiago_rasmussen14 points·8 months ago

Second this question. I have wondered about hypoglycaemia for 4 months and never seen a straight answer.

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u/cormac_danquah14 points·8 months ago

Slight fix: the number was 95.1, not 94.2. Decimal point, but a fairly consequential one.

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u/arne_nybergOP8 points·8 months ago

Slight fix: the number was 95.1, not 94.2.

Disagree on that part. 98.1% and 98.3% on the same vial is normal.

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u/ice_pack_auditcold chain42 points·8 months ago

The evidence standard in c/vendorvetting gets called too strict about once a month, and every time, the thread ends with the complainant agreeing.

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u/arne_amankwah32 points·8 months ago

glycaemic control first, that is the original indication

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u/a1c_arcT2D18 points·8 months ago

Slight fix: the number was 98.1, not 98.0. Decimal point, but a fairly consequential one.

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u/hugo_norgaard9 points·8 months ago

Slight fix: the number was 98.1, not 98.0.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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  1. Insulin and sulfonylurea interactions are a real hypo risk. Do not hand-wave them.
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