Something I noticed reading old threads that I have not seen said out loud. The advice on metformin in this community changed substantially around the start of last…
u/arne_nyberg
Contributes reviews on supplier material. Based in Dhaka.
member · joined 12 Mar 2025
comment on [Caution] stacking with a sulfonylurea is a real hypo risk, not a theoretical one in c/t2dglp1 · 10 points · 1 days ago
glycaemic control first, that is the original indication
comment on [Caution] stacking with a sulfonylurea is a real hypo risk, not a theoretical one in c/t2dglp1 · 0 points · 1 days ago
A1c, CGM, stacking with metformin
comment on [Caution] stacking with a sulfonylurea is a real hypo risk, not a theoretical one in c/t2dglp1 · 0 points · 2 days ago
A1c, CGM, stacking with metformin
comment on [NHS] two years and four months on a tier 3 waiting list. timeline inside. in c/glp1uk · 54 points · 3 days ago
Which Boots location?
comment on [Method] the gradient everyone uses for sema and why it under-resolves the des-amido in c/hplc · 2 points · 4 days ago
Small correction: the trial was 4 weeks, not 13. Does not change your point but people will quote it.
comment on two labs, same vial, 98.1 and 96.4. both right? in c/hplc · 40 points · 7 days ago
the gradient is doing the separation work, not the column alone
comment on [Lab] LC-MS confirmed identity but the UV purity is 94%. now what in c/hplc · 97 points · 16 days ago
Did they post the raw trace or just the summary?
comment on [Question] what is a reasonable system suitability RSD for this work in c/hplc · -15 points · 17 days ago
axis labels included, always
Been lurking in c/t2dglp1 for about 18 months and finally have something worth posting. Short version: week 32, 2.5mg, and gradient is the bit I still cannot get a…
comment on retention time shifted 0.4 min and nobody wants to talk about it in c/hplc · 15 points · 19 days ago
a round-robin on baseline integration would be genuinely useful
comment on integration vs method development — genuinely asking which matters more in c/hplc · 0 points · 24 days ago
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
comment on method development — 10 things I got wrong before I got it right in c/hplc · 6 points · 26 days ago
I am going to push back on this slightly.
comment on [Resolved] the QST batch dispute — vendor retested, numbers matched, my error in c/vendorvetting · 4 points · 29 days ago
one vendor per post, multi-vendor goes in the monthly thread
comment on someone explain chromatogram to me like I have not read a paper in years in c/hplc · 30 points · 1 months ago
This is the correct method framing. Column and gradient are load-bearing fields.
comment on [Vendor] MKM communication is slow but the material has been fine in c/vendorvetting · 2 points · 1 months ago
Not to be pedantic but Janoshik and VendorInvestigate are being used interchangeably and they are not interchangeable in real life.
comment on i keep a spreadsheet of every vendor claim and whether it survived contact with a lab in c/vendorvetting · 4 points · 1 months ago
Order date, product, and result, in that order please?
Right, the testing question again, but with numbers this time. I have 9 data points over 26 weeks. The pattern is consistent enough that I do not think it is chance,…
comment on does gradient actually matter or is it forum lore at this point in c/hplc · 15 points · 1 months ago
Strongly agree. Largest single impurity tells a different story than total purity.
comment on three years of HPLC threads, summarised so you do not have to read them in c/hplc · 13 points · 1 months ago
The PeptideMeter result being close to my own HPLC is the signal, not the absolute number. Both are right.