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c/t2dglp1·posted 1 year ago by u/iman_castellanos

does CGM actually matter or is it forum lore at this point

Caution Long Haul ×2 Cold Box ×3

I have had 21 orders now and I keep a table, so here is the honest summary rather than a vibe.

Material has been consistent. Communication has not. Shipping has varied by about 20 days on nominally the same lane, which matters more in summer than in February.

The independent number came back 93.7% against a claimed 98.6%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.

Batch number is in the comments. Ask if you want the method.

1,843 up / 79 down96% upvoted39 commentsid xhsnge27 Jul 2025

39 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/ice_pack_auditcold chain207 points·1 year ago

glycaemic control first, that is the original indication

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u/iman_castellanosOP157 points·1 year ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

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u/kaia_cabrera94 points·1 year ago

Not to be pedantic but glycaemic control and T2D are being used interchangeably and they are not interchangeable in real life.

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u/stubborn_batchlist_maybe120 points·1 year ago

You have restated the marketing copy. What is the actual substance here.

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u/neha_rahimi97 points·1 year ago

hypoglycaemia risk when stacked with metformin

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u/fasting_insulin_f-24 points·12 months ago

Not to be pedantic but glycaemic control and hypoglycaemia are being used interchangeably and they are not interchangeable in real life.

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u/ilias_kaufmann57 points·1 year ago

metformin combo is standard

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u/arne_nyberg15 points·12 months ago

The confident tone is doing a lot of work that the evidence is not.

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u/appeal_letter_al144 points·1 year ago

Yeah, glycaemic control is the original use.

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u/tired_ledger_notes38 points·1 year ago

CGM traces tell a story, numbers alone do not

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u/nils_ferreira27 points·1 year ago

Strongly agree. A1c matters as much as weight.

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u/iman_castellanosOP20 points·1 year ago

insulin and sulfonylurea interactions are real hypo risk

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u/arne_nyberg147 points·1 year ago

Titration speed is a side-effect dial far more than an efficacy dial.

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u/marta_weiss86 points·1 year ago

What was the batch number and which service?

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u/iman_castellanosOP35 points·1 year ago

Ireland here. Waited 18 months on a list, gave up, went private, and the total cost was roughly what I expected.

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u/lyophile_lou9 points·1 year ago

the weight-loss conversation drowns out glycaemic control sometimes

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u/plain_titration19 points·1 year ago

glycaemic control first, that is the original indication

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[deleted]32 points·1 year ago

[deleted]

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u/aleksi_eriksen26 points·12 months ago·edited

[deleted]

Adding to this: metformin is doing more work than the comment implies.

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u/fabio_lehtinen21 points·12 months ago

A1c, CGM, stacking with metformin

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u/joaquin_stanescu5 points·12 months ago

Not to be pedantic but hypoglycaemia and T2D are being used interchangeably and they are not interchangeable in real life.

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u/meal_prep_mira41 points·1 year ago

Came off after 89 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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u/a1c_arcT2D30 points·12 months ago

metformin combo is standard

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u/a1c_arcMOD50 points·1 year ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/tomas_lokken22 points·1 year ago

Genuine question — what concentration were you at?

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u/step_count_stan73 points·1 year ago

the 78 A1c trend is the answer

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u/bianca_dziedzic37 points·1 year ago

CGM traces tell a story, numbers alone do not

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u/nadia_norgaard29 points·1 year ago

CGM traces tell a story, numbers alone do not

Yes, exactly this, and it is the bit that took me 67 weeks to accept.

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About c/t2dglp1

Type 2 diabetes as the original indication: A1c trajectories, CGM traces, hypoglycaemia risk when stacked with sulfonylureas or insulin, metformin combinations, and why the weight-loss conversation sometimes drowns out the glycaemic one.

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c/t2dglp1 rules
  1. Insulin and sulfonylurea interactions are a real hypo risk. Do not hand-wave them.
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