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[Discussion] can we stop arguing about T2D until somebody posts a number
Been lurking in c/scamalerts for about 5 months and finally have something worth posting. Short version: week 95, 2.4mg, and A1c is the bit I still cannot get a…
u/ilias_kaufmann
Contributes reviews on supplier material. Based in Rijeka.
member · joined 15 Jun 2025
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comment on [Results] A1c 9.1 → 5.4, full table, 14 months in c/t2dglp1 · 7 points · 2 days ago
insulin and sulfonylurea interactions are real hypo risk
comment on [Sceptic] the tendon claims outran the evidence by about a decade in c/bpc157 · 10 points · 3 days ago
Came off after 68 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.
comment on [Trial Data] what the STEP 4 and SURMOUNT-4 withdrawal arms actually showed in c/tapering · 1 points · 5 days ago
Yeah, regain is not a failure.
comment on [Paper] receptor distribution and why the GI effects were predictable in c/glp1science · -21 points · 6 days ago
Yeah, the incretin mechanism is doing the work here.
comment on [Discussion] the weight conversation drowns out the glycaemic one in c/t2dglp1 · 9 points · 10 days ago
hypoglycaemia risk when stacked with A1c
comment on [Discussion] can we stop arguing about T2D until somebody posts a number in c/t2dglp1 · 19 points · 18 days ago
Maintenance for 9 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.
comment on co-agonism — my 4-week log, condensed into one table in c/cagrilintide · 1 points · 25 days ago
Yeah, amylin is doing different work than GLP-1.
comment on interval stretching is the most under-discussed thing in c/t2dglp1 in c/tapering · 19 points · 1 months ago
Strongly agree. The regain is expected.
comment on [Lab] SSA BPC — Medutest came back 97.4% against a claimed 96.2% in c/bpc157 · 6 points · 1 months ago
Mechanistically the bit that matters is regulatory. It explains most of the early profile and a decent chunk of the outcome.
comment on [Question] how do you actually verify amylin in c/cagrilintide · 138 points · 1 months ago
the mechanism is different, the side effect profile reflects it
comment on [Results] 7 weeks, 40kg, and contraception was the hard part in c/glp1women · 1 points · 2 months ago
Strongly agree. Cycle changes are documented.
comment on tried CagriSema for 2 weeks. here is what happened. in c/cagrilintide · 20 points · 2 months ago
That is net peptide content, not purity. Different number, different meaning.
comment on genuine question about incretin that I am slightly embarrassed to ask in c/glp1science · 26 points · 2 months ago
Strongly agree.
Adding to this: half-life is doing more work than the comment implies.
comment on [Question] rodent data — what am I missing here in c/bpc157 · 23 points · 2 months ago
handlers in the community are rare and cautious
comment on three years of regain threads, summarised so you do not have to read them in c/tapering · 2 points · 3 months ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on [Results] 87 weeks, 11kg, and interval stretching was the hard part in c/tapering · 91 points · 3 months ago
STEP 1 and SURMOUNT-4 discontinuation arms show regain
comment on [Results] 87 weeks, 11kg, and interval stretching was the hard part in c/tapering · 28 points · 3 months ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on three years of mechanism threads, summarised so you do not have to read them in c/glp1science · 36 points · 3 months ago
Half-life is about 168 hours, so steady state lands around week 21–5.
Adding to this: incretin is doing more work than the comment implies.
comment on interval stretching is the most under-discussed thing in c/compounding in c/tapering · 23 points · 4 months ago
Titration speed is a side-effect dial far more than an efficacy dial.