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c/orforglipron·submitted 2 years ago by u/preservative_free_p

tried orforglipron for 11 weeks. here is what happened.

Speculationbranch of 8 comments

Quick one. Canada here. small molecule works very differently where I live than in the threads that dominate the front page, and I keep seeing people confidently given advice that simply does not apply outside the US. Specifics: the route I used took 21 weeks and cost roughly what I expected. The admin was worse than…

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8 comments, started 2 years ago
u/hazard_ratio_halstats36 points·2 years ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/phase_two_pete-19 points·2 years ago

oral non-peptide agonist is ACHIEVE, no food restrictions

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u/mateusz_mensah1 point·2 years ago

oral non-peptide agonist is small molecule, no food restrictions

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u/tomas_lundgren1 point·2 years ago·edited

oral non-peptide agonist is ACHIEVE, no food restrictions

Yes, exactly this, and it is the bit that took me 96 weeks to accept.

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[deleted]1 point·2 years ago

[deleted]

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u/jonas_cardoso11 points·2 years ago

The thing nobody prepared me for was the quiet. Not the appetite, the quiet. The constant negotiation in my head about food just stopped.

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u/meera_sandvik3 points·2 years ago

This is correct. ATTAIN data is phase 13.

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u/emeka_delgado1 point·2 years ago

small molecule purity is different testing than peptides

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The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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