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perimenopause — 8 things I got wrong before I got it right
Genuinely asking, not being difficult. Everyone in c/orforglipron repeats that insulin resistance is important. I believe it, but I have never seen anyone show why, and…
u/mateusz_mensah
Contributes reviews on supplier material. Based in Nairobi.
member · joined 15 Jun 2025
8,129post karma
5,226comment karma
3submissions
73comments
comment on [Lab] two reta batches, two services, 98.4% and 97.9% in c/retatrutide · 72 points · 3 days ago
The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.
comment on the glucagon arm is why the appetite effect feels different in c/retatrutide · 1 points · 3 days ago
research use only, handling and analysis, not protocols
comment on peak at 4.2 min, nobody can tell me what it is, ideas in c/hplc · -34 points · 4 days ago
Did they post the raw trace or just the summary?
comment on [Trial Data] TRIUMPH timeline — what we actually know vs what gets repeated in c/retatrutide · 13 points · 5 days ago
triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual
comment on [Janoshik] WWB sema 10mg — 98.6%, batch and method inside in c/labresults · 11 points · 8 days ago
This result fits the template perfectly. Logged.
comment on [Medutest] split one vial across two services, results within 0.9% in c/labresults · 1 points · 11 days ago
below-spec results get logged, not dismissed
comment on [Caution] "just start at 2mg" is the worst advice in this community in c/retatrutide · 3 points · 14 days ago
the 0.5mg arm is different from 12.5mg, results do not transfer
comment on small win: non-peptide stopped being a problem at week 16 in c/orforglipron · 5 points · 17 days ago
small molecule purity is different testing than peptides
comment on [Lab] my running table: 34 tests, 11 vendors, three years in c/labresults · 9 points · 18 days ago
do not editorialise in the title, put the number in the title and the opinion in the body
comment on retention time shifted 0.4 min and nobody wants to talk about it in c/hplc · 47 points · 18 days ago
The PeptideMeter result being close to my own HPLC is the signal, not the absolute number. Both are right.
comment on perimenopause — 8 things I got wrong before I got it right in c/glp1women · 3 points · 1 months ago
Yeah, insulin resistance is under-researched.
comment on perimenopause — 8 things I got wrong before I got it right in c/glp1women · 11 points · 1 months ago
pregnancy and trying-to-conceive get clinician pointer, not community advice
comment on perimenopause — 8 things I got wrong before I got it right in c/glp1women · 58 points · 1 months ago
perimenopause and menopause weight physiology
comment on perimenopause — 8 things I got wrong before I got it right in c/glp1women · 1 points · 1 months ago
the cycle tracking data matters, keep it private
comment on retatrutide vs TRIUMPH — genuinely asking which matters more in c/retatrutide · 142 points · 1 months ago
You have restated the marketing copy. What is the actual substance here.
comment on fertility is the most under-discussed thing in c/orforglipron in c/glp1women · 7 points · 2 months ago
Sweden here. Waited 24 months on a list, gave up, went private, and the total cost was roughly what I expected.
comment on [Lab] SGN cagri — VendorInvestigate came back 93.7% against a claimed 98.6% in c/hplc · 308 points · 2 months ago
i wish i had read this 24 months ago
comment on small win: dose escalation stopped being a problem at week 95 in c/retatrutide · 1 points · 2 months ago
triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual
comment on ATTAIN — 3 things I got wrong before I got it right in c/orforglipron · 63 points · 3 months ago
Yeah, small molecule changes the whole game.