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c/orforglipron·posted 1 year ago by u/zeynep_ndiaye

[Discussion] ATTAIN is doing more work than we give it credit for

Discussion Receipts ×5 Well Actually ×3

Posting this because I searched for it and got nothing useful.

Setup: 0.5mg, week 64, sulphur burps present but not ruining anything. I changed exactly one variable — ATTAIN — and tracked it for 9 weeks.

Result: a difference, but a small one, and well inside what I would call noise if someone else posted it. So I am putting it here rather than presenting it as a finding. If two or three other people have done the same thing we might actually learn something.

Not medical advice, obviously. This is one person with a spreadsheet.

2,604 up / 61 down98% upvoted22 commentsid 1v8ifs18 Sep 2024

22 comments

11 in this archive, depth 5

best — the order this archive was captured in

u/sofia_petrescu208 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

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u/santiago_villalobos86 points·1 year ago

the supply conversation changes if this approves

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u/quiet_moderatormod188 points·1 year ago

The sulphur burps was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/sanne_delgado117 points·1 year ago

This is correct. ATTAIN data is phase 7.

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u/flair_enthusiast36 points·1 year ago

no cold chain means ATTAIN, if approved

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u/graph_it_gary-26 points·1 year ago

the fatigue profile is speculative at this stage

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u/quiet_moderatormod1 point·1 year ago·edited

phase 24 data is interesting, phase 34 will tell the real story

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u/sofia_petrescu1 point·1 year ago

oral non-peptide agonist is small molecule, no food restrictions

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[deleted]13 points·1 year ago

[deleted]

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u/tobias_molnar150 points·1 year ago

Came off after 23 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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u/zeynep_ndiayeOP67 points·1 year ago

phase 12 data is interesting, phase 6 will tell the real story

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About c/orforglipron

The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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