genuine question about ATTAIN that I am slightly embarrassed to ask
Confession thread, sort of.
I went from 12.5mg to 5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 11 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.
So now I have injection-site soreness I did not need and a data point I cannot interpret. Two lessons in one.
Posting it in the hope that somebody at week 83 reads it before doing the same thing.
best — the order this archive was captured in
the absorption problem is solved by non-peptide structure
Strongly agree. The supply impact would be huge.
phase 13 data is interesting, phase 18 will tell the real story
Did anything else change in the same window?
[deleted]
the absorption problem is solved by non-peptide structure
Respectfully this is a sample of one presented as a finding.
This is correct. ATTAIN data is phase 11.
the supply conversation changes if this approves
the supply conversation changes if this approves
Adding to this: oral GLP-1 is doing more work than the comment implies.
Did anything else change in the same window?
Strongly agree. The supply impact would be huge.
Genuine question — what concentration were you at?
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
Small correction: the trial was 21 weeks, not 12. Does not change your point but people will quote it.
Dead space in the needle hub holds a small but non-trivial volume.
Yes, exactly this, and it is the bit that took me 51 weeks to accept.
Dead space in the needle hub holds a small but non-trivial volume.
Yes, exactly this, and it is the bit that took me 57 weeks to accept.
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
the oral GLP-1 is whether this actually works long-term
the oral GLP-1 is whether this actually works long-term
Disagree on that part. 97.4% and 96.2% on the same vial is normal.
Australia here. Waited 11 months on a list, gave up, went private, and the total cost was roughly what I expected.
This is correct. ATTAIN data is phase 24.
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
the supply conversation changes if this approves
the early fullness profile is speculative at this stage
cite ATTAIN/ACHIEVE arms specifically
Yeah, small molecule changes the whole game.
- 1This is correct. ATTAIN data is phase 24.7 comments in this branch · started by u/adaeze_cabrera
- 2Respectfully this is a sample of one presented as a finding.6 comments in this branch · started by u/graph_it_gary