GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
crossposted from c/retatrutide by u/halima_mbeki — [Results] 2 weeks, 11kg, and glucagon was the hard part
Locked. A moderator closed replies on this one. It stays up because the content above the argument is worth keeping.
1k
c/glp1women·posted 9 months ago by u/aleksi_eriksen

tried PCOS for 16 weeks. here is what happened.

PCOS Receipts ×3 Cold Box ×1

Long-ish post, sorry. tl;dr at the bottom.

I have been tracking PCOS against eGFR for 15 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.

Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.

tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.

1,275 up / 231 down85% upvoted36 commentsid 7g6i0824 Oct 2025

36 comments

25 in this archive, depth 6

best — the order this archive was captured in

u/sulphur_burps_sue190 points·9 months ago
i have this exact spreadsheet
replysharereportpermalink
u/emeka_chowdhury-34 points·9 months ago

Yeah, insulin resistance is under-researched.

replysharereportpermalink
u/cesar_oyelaran1 point·9 months ago

the trials mostly studied men, insulin resistance skipped

replysharereportpermalink
[deleted]1 point·9 months ago

[deleted]

replysharereportpermalink
u/usp_appendixcompendial1 point·9 months ago

contraception interaction claims need citation

replysharereportpermalink
u/nayeli_iyer1 point·9 months ago

Yeah, contraception is under-researched.

replysharereportpermalink
u/jarno_karlsen1 point·9 months ago

Yeah, contraception is under-researched.

Adding to this: PCOS is doing more work than the comment implies.

replysharereportpermalink
u/lipid_panel_larrybloodwork1 point·9 months ago

Yeah, contraception is under-researched.

Yes, exactly this, and it is the bit that took me 79 weeks to accept.

replysharereportpermalink
u/careful_gradient1 point·9 months ago

contraception interaction claims need citation

replysharereportpermalink
u/signe_villalobos159 points·9 months ago·edited

Strongly agree. Cycle changes are documented.

replysharereportpermalink
u/nnt_nate105 points·9 months ago

pregnancy and trying-to-conceive get clinician pointer, not community advice

replysharereportpermalink
u/ewan_zielinski50 points·9 months ago
genuinely useful, thanks
replysharereportpermalink
u/mateusz_mensah33 points·9 months ago

contraception interaction claims need citation

replysharereportpermalink
u/devils_advocate_d42 points·9 months ago
yep. 9 weeks in, same.
replysharereportpermalink
u/low_appetite_lisaMOD16 points·9 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

replysharereportpermalink
u/blunt_coldbox_notes0 points·9 months ago

hair-loss on cycle is real

replysharereportpermalink
u/viktor_erdogan12 points·9 months ago

Stalled for 5 weeks, changed nothing, and it started moving again on week 92.

replysharereportpermalink
u/cesar_oyelaran32 points·9 months ago

Disagree. What you are describing is consistent with PCOS, not with what you concluded.

replysharereportpermalink
u/endotoxin_elliemicro8 points·9 months ago

Strongly agree. Cycle changes are documented.

replysharereportpermalink
u/cold_chromatogram9 points·9 months ago

no cycle-tracking data with identifying details

replysharereportpermalink
u/joaquin_wojcik28 points·9 months ago
it is in the wiki actually
replysharereportpermalink
u/aleksi_eriksenOP20 points·9 months ago

the UK here. Waited 20 months on a list, gave up, went private, and the total cost was roughly what I expected.

replysharereportpermalink
u/katrin_diallo15 points·9 months ago

contraception interaction claims need citation

replysharereportpermalink
u/yusuf_ramos16 points·9 months ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

replysharereportpermalink
u/forest_plot_fionastats8 points·9 months ago

fertility signal is there but unclear

replysharereportpermalink
Permalinked branches
Deep branches get their own page so a single reply chain can be linked and read on its own.
About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

48kmembers
62submissions
Jul 2024created
submissions / month, last year
Sponsored

PeptideMeter Analytics

Independent testing plus vendor-level trend data. Community-funded, unaffiliated.

peptidemeter.com
More in c/glp1women
c/glp1women rules
  1. Pregnancy and trying-to-conceive questions get a clinician pointer, not community advice.
  2. Contraception interaction claims need a citation.
  3. No cycle-tracking data with identifying details.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/hair_shed_hannahu/low_appetite_lisau/gentle_correctionu/wholesome_lurker
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →