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c/glp1women·posted 1 year ago by u/gustav_lindholm

7 months in and fertility is still the thing I get wrong

Caution Well Actually ×7 Sourced ×3 Clean Column ×2

contraception. That is the whole post, but I will justify it.

Everything else people worry about in c/glp1muscle is downstream of it. Titration speed, early fullness, the endless dose arguments — most of it resolves if you sort contraception out first, and almost nobody does.

I say this having got it wrong for 20 months. My eGFR was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.

3,969 up / 860 down82% upvoted65 commentsid 5sf6uc11 Sep 2024

65 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/gentle_correctionMOD642 points·1 year ago

Tracking number removed. It identifies both ends of a shipment.

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u/gustav_lindholmOP329 points·1 year ago

Came off after 50 weeks for financial reasons. Regained about a third over the following year. Back on now at a much lower dose.

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u/joaquin_trevino-13 points·1 year ago

Did anything else change in the same window?

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u/tl_dr_tina459 points·1 year ago

cycle changes are real and under-researched

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[deleted]178 points·1 year ago

[deleted]

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u/rasmus_petrescu138 points·1 year ago·edited

Strongly agree. Cycle changes are documented.

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u/careful_gradient104 points·1 year ago

pregnancy and trying-to-conceive get clinician pointer, not community advice

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u/pavel_kravchenko317 points·1 year ago

cycle changes are real and under-researched

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/dose_creep_dan218 points·1 year ago

hair-loss on contraception is real

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u/valeria_cardoso253 points·1 year ago

How many weeks between the two measurements?

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u/karim_restrepo78 points·1 year ago

perimenopause and menopause weight physiology

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u/lipid_panel_larrybloodwork237 points·1 year ago

Which country? Half the answers in this thread only apply in the Netherlands.

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u/dose_creep_dan83 points·1 year ago

This is correct. PCOS is real.

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u/valeria_cardoso133 points·1 year ago

Slight fix: the number was 99.0, not 98.9. Decimal point, but a fairly consequential one.

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u/careful_gradient156 points·1 year ago

I love that this community will spend 40 comments on a detail. That pedantry is why the numbers here matter.

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u/elodie_kuipers108 points·1 year ago

the cycle tracking data matters, keep it private

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u/micro_bump_mick32 points·1 year ago·edited

the cycle tracking data matters, keep it private

Disagree on that part. 99.2% and 99.3% on the same vial is normal.

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u/bastian_moreau19 points·1 year ago

Strongly agree. Cycle changes are documented.

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u/katrin_diallo9 points·1 year ago

cycle changes are real and under-researched

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u/coa_forgery_watch69 points·1 year ago

I love that this community will spend 40 comments on a detail.

Adding to this: fertility is doing more work than the comment implies.

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u/ilias_kaufmann29 points·1 year ago

Not to be pedantic but PCOS and insulin resistance are being used interchangeably and they are not interchangeable in real life.

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u/joaquin_wojcik12 points·1 year ago

Not to be pedantic but PCOS and insulin resistance are being used interchangeably and they are not interchangeable in real life.

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/kenji_demir4 points·1 year ago

That is net peptide content, not purity. Different number, different meaning.

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u/gustav_lindholmOP31 points·1 year ago

the cycle tracking data matters, keep it private

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u/kaia_fonseca132 points·1 year ago·edited

This is correct. PCOS is real.

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u/gustav_lindholmOP96 points·1 year ago

The sulphur burps was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/lukas_vermeulen66 points·1 year ago

PCOS and insulin resistance

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u/endotoxin_elliemicro83 points·1 year ago

the cycle tracking data matters, keep it private

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u/neha_rahimi61 points·1 year ago

Not to be pedantic but insulin resistance and PCOS are being used interchangeably and they are not interchangeable in real life.

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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  1. Pregnancy and trying-to-conceive questions get a clinician pointer, not community advice.
  2. Contraception interaction claims need a citation.
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