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c/glp1women·posted 1 year ago by u/dilara_szabo

help me understand PCOS, I have read the wiki twice

Caution Well Actually ×7 Clean Column ×2 Receipts ×2

Genuinely asking, not being difficult.

Everyone in c/darkspot repeats that insulin resistance is important. I believe it, but I have never seen anyone show why, and when I search I get 3 threads of people agreeing with each other.

Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?

I am not trying to be the "source?" guy. I would just like a source.

2,833 up / 206 down93% upvoted55 commentsid 44hkoi17 Jan 2025

55 comments

30 in this archive, depth 6

best — the order this archive was captured in

u/tired_ledger_ftw459 points·1 year ago

pregnancy and trying-to-conceive get clinician pointer, not community advice

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u/hair_shed_hannahMOD303 points·1 year ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/mei_cardoso211 points·1 year ago

PCOS and insulin resistance

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u/bastian_aalto294 points·1 year ago

contraception interaction claims need citation

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u/idris_kimani-36 points·1 year ago

the cycle tracking data matters, keep it private

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u/blunt_coldbox_20241 point·1 year ago

Yeah, contraception is under-researched.

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u/step_therapy_s99 points·1 year ago

pregnancy and trying-to-conceive get clinician pointer, not community advice

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u/dilara_szaboOP180 points·1 year ago

the trials mostly studied men, perimenopause skipped

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u/greta_nilsen188 points·1 year ago

perimenopause and menopause weight physiology

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u/rui_only_ro83 points·1 year ago

I am going to push back on this slightly.

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u/dilara_szaboOP50 points·1 year ago

The constipation was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/usp_appendixcompendial110 points·1 year ago

fertility signal is there but unclear

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u/santiago_villalobos46 points·1 year ago

perimenopause and menopause weight physiology

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u/aleksi_grimaldi11 points·1 year ago

What was the batch number and which service?

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u/step_therapy_s50 points·1 year ago

no cycle-tracking data with identifying details

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u/tared_twice74 points·1 year ago

Maintenance for 19 months now. Weight moves within about 3kg and the dose is a quarter of what it peaked at.

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u/ewan_tulloch88 points·1 year ago

This is correct. PCOS is real.

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u/column_dead_volume58 points·1 year ago

Slight fix: the number was 98.7, not 98.9. Decimal point, but a fairly consequential one.

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u/rasmus_petrescu47 points·1 year ago

contraception interaction claims need citation

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u/nils_tulloch36 points·1 year ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/nayeli_iyer55 points·1 year ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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[removed]41 points·1 year ago

[removed by moderator]

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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c/glp1women rules
  1. Pregnancy and trying-to-conceive questions get a clinician pointer, not community advice.
  2. Contraception interaction claims need a citation.
  3. No cycle-tracking data with identifying details.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
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