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c/glp1women·posted 1 year ago by u/emeka_chowdhury

[Question] perimenopause — what am I missing here

Question Clean Column ×9 Receipts ×2

Genuinely asking, not being difficult.

Everyone in c/darkspot repeats that insulin resistance is important. I believe it, but I have never seen anyone show why, and when I search I get 3 threads of people agreeing with each other.

Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?

I am not trying to be the "source?" guy. I would just like a source.

2,017 up / 292 down87% upvoted37 commentsid 16p1hl17 Mar 2025

37 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/georgi_haddad285 points·1 year ago·edited

contraception interaction claims need citation

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u/elin_lindqvist145 points·1 year ago

My version of this: I was so worried about the injection that I put it off for eleven days. The injection is the easiest part.

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u/bastian_eriksen-2 points·1 year ago

the trials mostly studied men, perimenopause skipped

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u/joaquin_wojcik1 point·1 year ago·edited

PCOS and insulin resistance

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u/zaid_roos1 point·1 year ago

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/foam_head_fred1 point·1 year ago

PCOS and insulin resistance

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u/devils_advocate_d1 point·1 year ago

This is correct. PCOS is real.

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u/karim_restrepo1 point·1 year ago

I am going to push back on this slightly.

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u/rina_sobczak1 point·1 year ago·edited

hormonal contraception interactions are speculative

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u/emeka_chowdhury1 point·1 year ago·edited

Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.

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u/karim_restrepo69 points·1 year ago·edited

Yeah, insulin resistance is under-researched.

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u/rasmus_petrescu21 points·1 year ago

Yeah, insulin resistance is under-researched.

Disagree on that part. 96.8% and 96.2% on the same vial is normal.

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u/jonas_cardoso43 points·1 year ago

hair-loss on contraception is real

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u/kenji_demir12 points·1 year ago

Week 5 for me and the honest summary is: 43kg down, sulphur burps manageable, and I have thought about food maybe four times today.

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u/rina_sobczak36 points·1 year ago

perimenopause and menopause weight physiology

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u/emeka_chowdhuryOP24 points·1 year ago

The constipation was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/rasmus_petrescu6 points·1 year ago

the cycle tracking data matters, keep it private

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u/sanne_novak2 points·1 year ago

Disagree. What you are describing is consistent with PCOS, not with what you concluded.

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u/ines_boateng26 points·1 year ago

hormonal contraception interactions are speculative

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u/kian_solberg12 points·1 year ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/emeka_chowdhuryOP14 points·1 year ago

Not convinced. The evidence does not support that reading.

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u/joaquin_trevino0 points·1 year ago

pregnancy and trying-to-conceive get clinician pointer, not community advice

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u/foam_head_fred9 points·1 year ago

This is correct. PCOS is real.

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u/sena_teixeira8 points·1 year ago

Genuine question — what concentration were you at?

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u/anders_karlsen6 points·1 year ago

the cycle tracking data matters, keep it private

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About c/glp1women

The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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