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c/glp1women·submitted 1 year ago by u/honest_syringe_2025

[Question] New Zealand — has anyone got a straight answer on insulin resistance

Questionbranch of 7 comments

Long-ish post, sorry. tl;dr at the bottom. I have been tracking PCOS against eGFR for 5 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here. Caveats up front: one person, one lab, one assay, no…

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7 comments, started 1 year ago
u/santiago_marchetti103 points·1 year ago

the cycle question is under-powered in trials

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u/gustav_lindholm-10 points·1 year ago

perimenopause and menopause weight physiology

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u/jarno_karlsen1 point·1 year ago

Not to be pedantic but PCOS and insulin resistance are being used interchangeably and they are not interchangeable in real life.

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u/ilias_kaufmann1 point·1 year ago

Strongly agree. Cycle changes are documented.

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u/endotoxin_elliemicro35 points·1 year ago

hair-loss on PCOS is real

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u/devils_advocate_d19 points·1 year ago

hair-loss on PCOS is real

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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