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c/coldchain·posted 9 months ago by u/soren_yildiz

[Meta] proposal — a flair for packaging posts

Data Well Actually ×2 Slow Clap ×1

Genuinely asking, not being difficult.

Everyone in c/glp1aus repeats that stability is important. I believe it, but I have never seen anyone show why, and when I search I get 8 threads of people agreeing with each other.

Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?

I am not trying to be the "source?" guy. I would just like a source.

2,160 up / 351 down86% upvoted45 commentsid tp2j7u17 Oct 2025

45 comments

30 in this archive, depth 4

best — the order this archive was captured in

u/ice_pack_auditcold chain121 points·9 months ago

The gel pack lasted 17 hours in a courier van, then liquid. Powder itself fine, the cold chain mostly died in transit.

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u/spain_receta-19 points·9 months ago

Do you have the logger trace?

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u/niels_norgaard1 point·9 months ago

lyophilised powder is far more forgiving than reconstituted solution

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u/curious_panel_only1 point·9 months ago·edited

Peak temperature and how long at that temperature?

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u/andres_restrepo99 points·9 months ago

Every time this gets posted it hits the front page and every time someone has to re-explain it.

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u/honest_syringe3334 points·9 months ago

The confident tone is doing a lot of work that the evidence is not.

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u/cato_batista19 points·9 months ago

Which carrier and route?

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u/ms_fragmenter58 points·9 months ago

Strongly agree. Peak temperature is not the whole story.

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u/reship_roulette19 points·9 months ago·edited

Respectfully this is a sample of one presented as a finding.

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u/runa_wikstrom56 points·9 months ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/hamza_weiss37 points·9 months ago

Yeah, data logger is the only acceptable proof.

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u/sterile_field_steph10 points·9 months ago

no tracking numbers, no full addresses, no label photos — instant removal

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u/india_generic_g34 points·9 months ago

This is correct. Dry powder is way more robust than liquid.

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u/creatine_and_cardio8 points·9 months ago

Slight fix: the number was 97.6, not 95.1. Decimal point, but a fairly consequential one.

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u/source_or_silence3 points·9 months ago

no tracking numbers, no full addresses, no label photos — instant removal

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[removed]5 points·9 months ago

[removed by moderator]

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u/split_dose_sceptic3 points·9 months ago

lyophilised powder is far more forgiving than reconstituted solution

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u/usb_logger_ursula10 points·9 months ago

Yeah, data logger is the only acceptable proof.

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u/soren_yildizOP4 points·9 months ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

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u/emil_marchand28 points·9 months ago

Strongly agree. Peak temperature is not the whole story.

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u/careful_gradient_again12 points·9 months ago

Spain to Spain: 15 days with SWB and 26 days with MKM. Same route, different carriers, variance is real.

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u/soren_yildizOP9 points·9 months ago

customs clearance often breaks the cold chain, factor that in

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u/niels_yilmaz8 points·9 months ago

stability after excursion is not zero, it is dose-dependent

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u/honest_syringe3315 points·9 months ago

customs clearance often breaks the cold chain, factor that in

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u/tomas_lokken24 points·9 months ago

Yeah, data logger is the only acceptable proof.

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About c/coldchain

Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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