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c/coldchain·posted 2 years ago by u/split_dose_sceptic

[Meta] proposal — a flair for cold chain posts

Data Well Actually ×5 Clean Column ×3 Receipts ×3

Genuinely asking, not being difficult.

Everyone in c/compounding repeats that data logger is important. I believe it, but I have never seen anyone show why, and when I search I get 13 threads of people agreeing with each other.

Is there a paper? Is there a measurement? Or is this one of those things that is true because it has been repeated since 2023?

I am not trying to be the "source?" guy. I would just like a source.

7,306 up / 2,804 down72% upvoted26 commentsid rr25v229 Jul 2024

26 comments

23 in this archive, depth 4

best — the order this archive was captured in

u/osman_eriksen773 points·2 years ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

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u/intent_to_treat923 points·2 years ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

Adding to this: data logger is doing more work than the comment implies.

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u/curious_panel_only507 points·2 years ago

Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.

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u/cato_batista349 points·1 year ago

Do you have the logger trace?

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u/aleksi_eriksen187 points·1 year ago

Disagree. What you are describing is consistent with excursion, not with what you concluded.

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u/nayeli_iyer135 points·1 year ago

Strongly agree. Peak temperature is not the whole story.

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u/iman_castellanos72 points·1 year ago

Logger trace from my shipment: 5 hours at 13°C. Powder tested 99.1% against 98.4% claim. Tolerates more than the box implies.

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u/mod_cold_roomMOD133 points·1 year ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/hamza_weiss101 points·1 year ago

Customs clearance took 6 days. Package sat unrefrigerated during that. Powder tested clean after, reconstituted solution probably would not have.

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[removed]65 points·1 year ago

[removed by moderator]

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u/bruno_dumitru34 points·1 year ago

Customs clearance took 6 days.

Adding to this: packaging is doing more work than the comment implies.

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u/split_dose_scepticOP60 points·1 year ago

Yeah, data logger is the only acceptable proof.

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u/split_dose_scepticOP0 points·1 year ago

Logger trace from my shipment: 23 hours at 15°C. Powder tested 98.6% against 99.0% claim. Tolerates more than the box implies.

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u/sequence_checkerresearch peptides86 points·1 year ago

Reconstituted or dry powder?

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u/split_dose_sceptic54 points·1 year ago·edited

lyophilised powder is far more forgiving than reconstituted solution

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u/transit_variance15 points·1 year ago

Small correction: the trial was 23 weeks, not 28. Does not change your point but people will quote it.

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u/split_dose_scepticOP25 points·1 year ago

Denmark to Denmark: 24 days with SSA and 6 days with JEEP. Same route, different carriers, variance is real.

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u/nayeli_iyer82 points·1 year ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

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u/preservative_free_p76 points·2 years ago

Yeah, data logger is the only acceptable proof.

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u/nils_ferreira47 points·2 years ago

stability after excursion is not zero, it is dose-dependent

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u/preservative_free_p19 points·1 year ago

time-at-temperature integral is the dose, not just peak temperature

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u/split_dose_sceptic53 points·1 year ago

customs clearance often breaks the cold chain, factor that in

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u/mod_cold_roommod · c/coldchain26 points·1 year ago

Strongly agree. Peak temperature is not the whole story.

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About c/coldchain

Temperature and stability in the real world: what an excursion actually costs you, why lyophilised powder is far more forgiving than reconstituted solution, how to read a logger CSV, and how to photograph a failed shipment so the conversation with the vendor is short.

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c/coldchain rules
  1. Excursion claims need a logger trace or a photo taken at unboxing. "It felt warm" is not data.
  2. No tracking numbers, ever. They identify you and the recipient.
  3. Stability claims need a source or an explicit "this is my guess" label.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
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