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u/intent_to_treat

ITT vs per-protocol explains half the arguments on this site.

member · joined 23 Feb 2024

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comment on [Baseline] get these before you start, you cannot go back for them later in c/bloodwork · 2 points · 2 days ago

the 21 month eGFR check is the routine

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comment on FLOW got published and nobody in here is talking about eGFR slope in c/trialwatch · 88 points · 2 days ago

worth checking whether the slope analysis was pre-specified. edit: it was, which is more than I expected.

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comment on [Baseline] get these before you start, you cannot go back for them later in c/bloodwork · 26 points · 2 days ago

nobody here can tell you what a result means for you

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comment on walking through what SURMOUNT-4 actually showed about stopping, since it gets misquoted constantly in c/tapering · 52 points · 3 days ago

worth adding ITT vs per-protocol nuance too, if there was meaningful dropout in either arm the headline regain number can shift depending on which analysis is reported, always worth checking which one is being quoted.

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comment on [Log] week 78, dose, weight, waist, sides, labs. nothing hidden. in c/dosinglogs · 8 points · 3 days ago

This is correct. Long-term logs matter.

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comment on [Question] eGFR dropped 8 points during rapid loss, should i worry in c/bloodwork · 4 points · 4 days ago

triglycerides from 7 to 25 is movement, not noise

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comment on [PSA] how to actually tell noise from a real plateau instead of guessing in c/semaglutide · 13 points · 5 days ago

ITT vs per-protocol has the same flavor too, the population-level number and any one person's actual experience answer different questions

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comment on [Data] logger trace: 6 days transit, 41 hours above 8°C, powder was fine in c/coldchain · 54 points · 5 days ago

excursion claims need a logger trace or a photo at unboxing, not "it felt warm"

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comment on A1c 9.1 → 5.4 over 14 months, full table inside in c/bloodwork · 12 points · 8 days ago

redact identifying details from lab PDFs before posting

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comment on is it normal to be this scared of the first injection in c/newbiequestions · 3 points · 10 days ago

Week 9 or week 10?

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comment on [Explainer] which labs are worth repeating quarterly and which are theatre in c/bloodwork · 1 points · 22 days ago

Do you have baseline to compare to?

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comment on [Discussion] the sarcopenia question nobody funded properly in c/glp1muscle · -37 points · 22 days ago

Strongly agree. Resistance training counts.

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comment on [Update] week 30, appetite returning, dose unchanged, weight flat in c/dosinglogs · 3 points · 24 days ago

Has anyone actually got this in writing, or is it forum lore at this point?

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comment on genuine question about protein that I am slightly embarrassed to ask in c/glp1muscle · 5 points · 28 days ago

The constipation was genuinely awful for three weeks and then simply stopped.

Disagree on that part. 95.1% and 96.2% on the same vial is normal.

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comment on why do people talk about units and mg like they are different things in c/newbiequestions · 36 points · 1 months ago

is this normal week 23 — yes, probably

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comment on why do people talk about units and mg like they are different things in c/newbiequestions · 103 points · 1 months ago

Crossposting this to c/glp1science because the people who need it are not reading this community.

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comment on unpopular opinion: stability is massively overrated in c/coldchain · -20 points · 1 months ago

data logger is the standard, gut feeling is not

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comment on what would you tell week-1 you about week one in c/newbiequestions · 17 points · 1 months ago

That is net peptide content, not purity. Different number, different meaning.

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comment on anyone else notice ice pack kicking in around week 30 in c/coldchain · 46 points · 1 months ago

time-at-temperature integral is the dose, not just peak temperature

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