tried CagriSema for 12 weeks. here is what happened.
I have had 8 orders now and I keep a table, so here is the honest summary rather than a vibe.
Material has been consistent. Communication has not. Shipping has varied by about 40 days on nominally the same lane, which matters more in summer than in February.
The independent number came back 96.8% against a claimed 99.1%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.
Batch number is in the comments. Ask if you want the method.
best — the order this archive was captured in
This is the "correlation is mechanism" thing again. You changed three variables at once.
tendon and CagriSema literature in rodents is interesting
long-acting amylin is CagriSema, different satiety profile
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
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Sceptical. If this were true we would see it reflected in the data and we do not.
the mechanism is different, the side effect profile reflects it
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
not approved anywhere, keep posts descriptive, not instructional
Strongly agree. REDEFINE is phase 15, not final.
the co-agonism question is real and interesting
Slight fix: the number was 99.1, not 93.7. Decimal point, but a fairly consequential one.
Slight fix: the number was 99.1, not 93.7.
Adding to this: REDEFINE is doing more work than the comment implies.
Small correction: the trial was 8 weeks, not 5. Does not change your point but people will quote it.
Every time this gets posted it hits the front page and every time someone has to re-explain it.
Strongly agree. REDEFINE is phase 14, not final.
Every time this gets posted it hits the front page and every time someone has to re-explain it.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
REDEFINE readouts are phase 8 data
Tracking number removed. It identifies both ends of a shipment.
Not to be pedantic but satiety and REDEFINE are being used interchangeably and they are not interchangeable in real life.
- 1Rodent data is rodent data. Dose scaling is not linear and the models tell…6 comments in this branch · started by u/zeynep_zielinski
- 2nope. mine was the opposite.6 comments in this branch · started by u/teodor_lokken