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Single comment threadYou are looking at one branch of tried CagriSema for 12 weeks. here is what happened. — 27 comments in the full submission. View in context.
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c/cagrilintide·submitted 1 year ago by u/noor_vermeulen

tried CagriSema for 12 weeks. here is what happened.

Cautionbranch of 6 comments

I have had 8 orders now and I keep a table, so here is the honest summary rather than a vibe. Material has been consistent. Communication has not. Shipping has varied by about 40 days on nominally the same lane, which matters more in summer than in February. The independent number came back 96.8% against a claimed…

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6 comments, started 1 year ago
u/teodor_lokken37 points·1 year ago
nope. mine was the opposite.
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u/noor_vermeulenOP22 points·1 year ago

Strongly agree. REDEFINE is phase 15, not final.

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u/zeynep_zielinski12 points·1 year ago·edited

the co-agonism question is real and interesting

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u/niels_norgaard14 points·1 year ago

Slight fix: the number was 99.1, not 93.7. Decimal point, but a fairly consequential one.

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u/amara_kuipers3 points·1 year ago

Slight fix: the number was 99.1, not 93.7.

Adding to this: REDEFINE is doing more work than the comment implies.

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u/rina_sobczak6 points·1 year ago

Small correction: the trial was 8 weeks, not 5. Does not change your point but people will quote it.

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Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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