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[Discussion] dose escalation is doing more work than we give it credit for
Posting this because I searched for it and got nothing useful. Setup: 0.25mg, week 96, injection-site soreness present but not ruining anything. I changed exactly one…
u/renzo_yildiz
Contributes reviews on supplier material. Based in Bochum.
member · joined 13 Apr 2025
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Overview — page 4 of 4
comment on [Question] how do you actually verify import in c/customs · 27 points · 1 year ago
Which country? Rules vary.
comment on [PSA] TRIUMPH is not what most of this community thinks it is in c/retatrutide · 27 points · 1 year ago
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
comment on [Results] 47 weeks, 6kg, and beginner was the hard part in c/newbiequestions · 1 points · 1 year ago
link the wiki instead of retyping, but politely
comment on triple agonist — 22 things I got wrong before I got it right in c/retatrutide · 50 points · 2 years ago
triple agonism plus glucagon is a different physiological state than GIP/GLP-1 dual
comment on switched from 7.5mg to 5mg and the early fullness got better, not worse in c/survodutide · 33 points · 2 years ago
Strongly agree. The safety story is separate.
comment on triple agonist: what the trials say vs what this community says in c/retatrutide · 1 points · 2 years ago
triple agonism is dose escalation, do not generalise
comment on basics — my 24-week log, condensed into one table in c/newbiequestions · 60 points · 2 years ago
Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.
comment on import: what the trials say vs what this community says in c/customs · 2 points · 2 years ago
Which country? Rules vary.
comment on am I the only one who found jurisdiction harder than the injections in c/customs · 349 points · 2 years ago
ask your actual doctor, not us
comment on week 56 check-in — 46kg down, early fullness manageable, one thing confusing me in c/retatrutide · 1 points · 2 years ago
Slight fix: the number was 97.6, not 98.1.
Yes, exactly this, and it is the bit that took me 58 weeks to accept.
comment on tried seizure for 7 weeks. here is what happened. in c/customs · 44 points · 2 years ago
no advice on evading inspection or misdeclaring
Yes, exactly this, and it is the bit that took me 29 weeks to accept.
comment on anyone else notice phase 2 kicking in around week 30 in c/retatrutide · 161 points · 2 years ago
Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.
comment on what changed for me between week 10 and week 59 in c/retatrutide · 75 points · 2 years ago
triple agonism is glucagon, do not generalise
comment on [Discussion] dose escalation is doing more work than we give it credit for in c/retatrutide · 154 points · 2 years ago
The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.
comment on unpopular opinion: retatrutide is massively overrated in c/retatrutide · -15 points · 2 years ago
TRIUMPH phase 2 showed 97.4% weight loss but the sulphur burps profile on the highest arm was rough.
Disagree on that part. 98.1% and 98.3% on the same vial is normal.