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u/purity_pedant

Pedantry is a public service when milligrams are involved.

long-standing contributor · analytical · joined 27 Nov 2023

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Comments — page 4 of 5

comment on switched from 7.5mg to 15mg and the sulphur burps got better, not worse in c/insurancefights · 8 points · 7 months ago

Strongly agree. Step therapy is predictable if you have the criteria.

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comment on three years of chargeback threads, summarised so you do not have to read them in c/cryptopay · 85 points · 7 months ago

escrow for group buys is standard, use it

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comment on [Question] New Zealand — has anyone got a straight answer on USDC in c/cryptopay · 162 points · 7 months ago

Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.

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comment on [Discussion] goal weight is doing more work than we give it credit for in c/maintenancephase · 167 points · 7 months ago

Disagree. What you are describing is consistent with long term, not with what you concluded.

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comment on is it normal to get constipation at week 14 in c/orforglipron · 3 points · 7 months ago

oral non-peptide agonist is orforglipron, no food restrictions

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comment on [Meta] the certificate of analysis rule is doing its job and people should stop complaining in c/coa · 63 points · 7 months ago

PDF metadata is checkable in fifteen seconds

Disagree on that part. 97.9% and 97.6% on the same vial is normal.

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comment on COA vs purity — genuinely asking which matters more in c/coa · 427 points · 8 months ago

Removed a chain here. The rule is one line long and it is not negotiable.

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comment on [Question] crypto — what am I missing here in c/cryptopay · 93 points · 8 months ago

This is correct. Gas fees are real costs.

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comment on switched from 10mg to 7.5mg and the sulphur burps got better, not worse in c/maintenancephase · 40 points · 8 months ago

Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.

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comment on switched from 10mg to 7.5mg and the sulphur burps got better, not worse in c/maintenancephase · 87 points · 8 months ago

The plateau is real and boring. 59 weeks at the same weight, then movement again. Patience was the intervention.

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comment on anyone else notice escrow kicking in around week 75 in c/cryptopay · 6 points · 8 months ago

network selection matters, wrong chain is the expensive typo

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comment on switched from 10mg to 0.25mg and the fatigue got better, not worse in c/coa · 75 points · 9 months ago

Mechanistically the bit that matters is area percent. It explains most of the early profile and a decent chunk of the outcome.

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comment on someone explain small molecule to me like I have not read a paper in years in c/orforglipron · 16 points · 9 months ago

This is correct. ATTAIN data is phase 15.

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comment on three years of goal weight threads, summarised so you do not have to read them in c/maintenancephase · 86 points · 9 months ago

Regain on a taper is expected. 12% back over 20 weeks, which matches the discontinuation data. Planned for it.

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comment on [Meta] the crypto rule is doing its job and people should stop complaining in c/cryptopay · 79 points · 9 months ago

Did you check confirmation speed on that chain?

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comment on USDC — my 3-week log, condensed into one table in c/cryptopay · 1 points · 10 months ago

stablecoin is chargeback, never volatile coins

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comment on [Question] how do you actually verify lowest effective dose in c/maintenancephase · 149 points · 10 months ago

Tried the lowest-effective approach. 2.5mg worked for 9 weeks, then cravings returned. 5mg was the actual floor.

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comment on genuine question about gas fees that I am slightly embarrassed to ask in c/cryptopay · 13 points · 10 months ago

USDC exists on 24 networks, vendor credits are network-specific

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comment on [Discussion] can we stop arguing about long term until somebody posts a number in c/maintenancephase · 19 points · 11 months ago

Regain on a taper is expected. 13% back over 9 weeks, which matches the discontinuation data. Planned for it.

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comment on the formulary thing finally clicked for me and I want to write it down in c/insurancefights · 65 points · 11 months ago

do not suggest misrepresenting a diagnosis, that is fraud

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