u/incretin_ivy
GIP/GLP-1 co-agonism is genuinely interesting pharmacology, separate from the weight story.
long-standing contributor · pharmacology · joined 8 Jul 2024
Comments — page 5 of 5
comment on does lost money actually matter or is it forum lore at this point in c/darkspot · -2 points · 2 months ago
the 4 order that disappeared from SSA
comment on [Vendor] WXT order #24 — Germany, 21 days, no drama, receipts inside in c/retatrutide · 4 points · 2 months ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on tried CagriSema for 2 weeks. here is what happened. in c/cagrilintide · 11 points · 2 months ago
the mechanism is different, the side effect profile reflects it
comment on [Question] Sweden — has anyone got a straight answer on GIP in c/tirzepatide · 8 points · 2 months ago
Tracking number removed. It identifies both ends of a shipment.
comment on pharmacology is the most under-discussed thing in c/glp1women in c/glp1science · 4 points · 2 months ago
This is correct.
Yes, exactly this, and it is the bit that took me 77 weeks to accept.
comment on [Discussion] the formulary advice in here is 4 years out of date in c/glp1canada · 2 points · 2 months ago
Stalled for 8 weeks, changed nothing, and it started moving again on week 88.
comment on switched from 0.25mg to 1.7mg and the constipation got better, not worse in c/maintenancephase · 142 points · 2 months ago
Tried the lowest-effective approach. 1.7mg worked for 14 weeks, then cravings returned. 12.5mg was the actual floor.
comment on [Meta] the survodutide rule is doing its job and people should stop complaining in c/survodutide · 58 points · 2 months ago
Phase 20 or 15?
comment on switched from 1.0mg to 2.5mg and the the food-noise thing got better, not worse in c/tirzepatide · 22 points · 2 months ago
Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.
comment on switched from 1.0mg to 2.5mg and the the food-noise thing got better, not worse in c/tirzepatide · 5 points · 2 months ago
How long at each step before you escalated?
comment on [Meta] the retatrutide rule is doing its job and people should stop complaining in c/retatrutide · 35 points · 2 months ago
Three years on this site and the questions have not changed at all. Which is depressing or reassuring depending on the day.
comment on does orforglipron actually matter or is it forum lore at this point in c/orforglipron · 4 points · 2 months ago
phase 22 data is interesting, phase 16 will tell the real story
comment on am I the only one who found hepatic fat harder than the injections in c/survodutide · 7 points · 2 months ago
Retitled to remove editorialising. Put the evidence in the body.
comment on help me understand long term, I have read the wiki twice in c/maintenancephase · 1 points · 2 months ago
Tried the lowest-effective approach. 1.0mg worked for 9 weeks, then cravings returned. 2.4mg was the actual floor.
comment on help me understand incretin, I have read the wiki twice in c/glp1science · 15 points · 2 months ago
Where does the receptor data actually come from?
comment on help me understand incretin, I have read the wiki twice in c/glp1science · 105 points · 2 months ago
Stomach physiology changed when I moved up to 2.4mg. Gastric emptying lag is the whole story.
comment on help me understand incretin, I have read the wiki twice in c/glp1science · 35 points · 2 months ago
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
comment on help me understand incretin, I have read the wiki twice in c/glp1science · 22 points · 2 months ago
The half-life is 18 hours, which means week 18 is genuinely still ramp-up. Week 7 is steady state.
comment on [Results] 31 weeks on 5mg, full numbers, ask me anything boring in c/compounding · 6 points · 2 months ago
API source questions are on-topic and compounders dodging them is newsworthy
comment on small win: dose escalation stopped being a problem at week 95 in c/retatrutide · 3 points · 2 months ago
Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.