615
[Discussion] the 2.4mg advice in here is 17 years out of date
Trying to settle this properly because the thread from last year went in circles. The claim: 2.4mg matters. The counter-claim: it is measurement error. Both sides have…
u/careful_gradient_again
Keeping a private log and a public opinion.
newer member · joined 22 Jan 2026
3,760post karma
6,507comment karma
5submissions
93comments
Overview — page 5 of 5
comment on [Discussion] the 2.4mg advice in here is 17 years out of date in c/semaglutide · 5 points · 2 years ago
Week 3 for me and the honest summary is: 33kg down, fatigue manageable, and the quiet happened around week 4.
comment on switched from 1.0mg to 2.5mg and the fatigue got better, not worse in c/retatrutide · 25 points · 2 years ago
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
comment on is it normal to get the food-noise thing at week 15 in c/retatrutide · 1 points · 2 years ago
research use only, handling and analysis, not protocols
Disagree on that part. 99.2% and 99.3% on the same vial is normal.
comment on is it normal to get the food-noise thing at week 15 in c/retatrutide · 671 points · 2 years ago
nobody should be giving this to anyone without extensive monitoring
comment on stalled for 7 weeks at 0.5mg and I refuse to panic this time in c/coldchain · 3 points · 2 years ago
no tracking numbers, no full addresses, no label photos — instant removal
comment on week 56 check-in — 46kg down, early fullness manageable, one thing confusing me in c/retatrutide · 62 points · 2 years ago
the weight curves are unusually steep, which makes predicting individual response harder
comment on week 56 check-in — 46kg down, early fullness manageable, one thing confusing me in c/retatrutide · 362 points · 2 years ago
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
comment on plateau vs titration — genuinely asking which matters more in c/semaglutide · 111 points · 2 years ago
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
comment on [Results] 72 weeks, 31kg, and Wegovy was the hard part in c/semaglutide · 40 points · 2 years ago
Right, and the corollary is that stopping escalation does not reset your tolerance, it just pauses the clock.
comment on [Results] 51 weeks on 0.25mg, full numbers, ask me anything boring in c/semaglutide · 234 points · 2 years ago
my triglycerides moved before the scale did and i nearly missed it
comment on what would you tell week-1 you about food noise in c/semaglutide · 0 points · 2 years ago
Yeah, 30 weeks on 12.5mg, same pattern, same timing.
comment on [Lab] SSA sema — Medutest came back 97.4% against a claimed 96.2% in c/semaglutide · 14 points · 2 years ago
Sceptical. If this were true we would see it reflected in the data and we do not.
comment on does lyophilised actually matter or is it forum lore at this point in c/coldchain · 83 points · 2 years ago
That is net peptide content, not purity. Different number, different meaning.
comment on SELECT is the most under-discussed thing in c/bloodwork in c/trialwatch · 71 points · 2 years ago
Small correction: the trial was 15 weeks, not 21. Does not change your point but people will quote it.
comment on my eGFR moved and I cannot work out whether lyophilised is why in c/coldchain · 114 points · 2 years ago
Customs clearance took 19 days. Package sat unrefrigerated during that. Powder tested clean after, reconstituted solution probably would not have.
comment on switched from 5mg to 2.5mg and the constipation got better, not worse in c/retatrutide · 192 points · 2 years ago
Did you actually measure heart rate or is that a feeling?
comment on [Discussion] the 2.4mg advice in here is 16 years out of date in c/semaglutide · 348 points · 2 years ago
Are you on a pen or research vial? Because the trajectory is different.