switched from 1.0mg to 2.5mg and the fatigue got better, not worse
Long-ish post, sorry. tl;dr at the bottom.
I have been tracking retatrutide against ApoB for 19 weeks because I could not find anyone who had. The correlation is weaker than I expected, which is itself mildly interesting given how confidently people link the two in here.
Caveats up front: one person, one lab, one assay, no control, and I changed my training in the middle of it, which was stupid.
tl;dr: probably real, definitely smaller than the threads imply, and not worth reorganising your week around.
best — the order this archive was captured in
This is correct. Triple agonism is genuinely different.
Dose escalation on retatrutide is steeper and faster than on semaglutide. Do not assume the titration patterns transfer.
I am going to push back on this slightly.
heart rate and dose escalation need actual measurements, not impressions
retatrutide is not approved anywhere for human use, posts must not read as instructions
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
Dose escalation on retatrutide is steeper and faster than on semaglutide.
Yes, exactly this, and it is the bit that took me 4 weeks to accept.
Flair changed to match the content. Read the sidebar before posting next time and we are square.
the glucagon component changes the side effect profile, not just the efficacy
the glucagon component changes the side effect profile, not just the efficacy
I am going to push back on this slightly.
heart rate and dose escalation need actual measurements, not impressions
heart rate and dose escalation need actual measurements, not impressions
Yes, exactly this, and it is the bit that took me 82 weeks to accept.
the glucagon component changes the side effect profile, not just the efficacy
Dead space in the needle hub holds a small but non-trivial volume. On low-volume draws that can be several units.
phase 2 numbers are not maintenance numbers, cite the trial
Yeah, phase 2 retatrutide is interesting but it is not comparable to phase 3 compounds.
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
retatrutide is not approved anywhere for human use, posts must not read as instructions
retatrutide is not approved anywhere for human use, posts must not read as instructions
Adding to this: TRIUMPH is doing more work than the comment implies.
phase 2 numbers are not maintenance numbers, cite the trial
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
the dosing is steep, the nausea reports are real, and nobody knows the human safety yet
The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.
What was the dosing schedule in that arm?
the dosing is steep, the constipation reports are real, and nobody knows the human safety yet
What was the dosing schedule in that arm?
the 7.5mg arm is different from 5mg, results do not transfer
- 1Dead space in the needle hub holds a small but non-trivial volume. On…10 comments in this branch · started by u/reflux_report
- 2This is correct. Triple agonism is genuinely different.7 comments in this branch · started by u/farid_molnar