[Vendor] WXT order #2 — France, 33 days, no drama, receipts inside
Trying to settle this properly because the thread from last year went in circles.
The claim: SURMOUNT matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 20 months without either producing anything.
What would actually settle it is 19 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.
If you have data, post the data. If you have an opinion, flair it as an opinion.
best — the order this archive was captured in
do not crack the pen, we have been over this
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
That is net peptide content, not purity. Different number, different meaning.
the GIP side does different things than the GLP-1 side, that is the point
This matches the trial data. SURMOUNT-1 was 98.0% body weight at 6 weeks.
Every time this gets posted it hits the front page and every time someone has to re-explain it.
the GIP side does different things than the GLP-1 side, that is the point
Strongly agree. Tirz is better than sema is not a claim without a comparator dose.
dual agonism is SURPASS, do not generalise from semaglutide
This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.
Did you stay on semaglutide or switch? The outcome is different if you are comparing.
Did you stay on semaglutide or switch?
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
The confident tone is doing a lot of work that the evidence is not.
the the food-noise thing from tirz is different, not necessarily worse
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stalled on sema, tried tirz, and the curves were actually different shapes
stalled on sema, tried tirz, and the curves were actually different shapes
Yes, exactly this, and it is the bit that took me 10 weeks to accept.
SURMOUNT data is messier than STEP data but the weight loss is there
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
Water content matters more than people think. If a vial is carrying residual moisture, your "10mg" is not 10mg of peptide.
Inter-lab variance on this kind of assay is routinely 1–2 points. Different column, different gradient, different integration.
the nausea from tirz is different, not necessarily worse
Zepbound and Mounjaro are literally the same drug, the name is the only difference
Hard agree. The food noise disappears differently on the two compounds.
stalled on sema, tried tirz, and the curves were actually different shapes
the 15mg is the top of the pen, not the required dose
week 78 on Mounjaro and the appetite profile is genuinely different from sema
Did you stay on semaglutide or switch? The outcome is different if you are comparing.
do not crack the pen, we have been over this
do not crack the pen, we have been over this
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
- 1Every time this gets posted it hits the front page and every time someone…7 comments in this branch · started by u/elin_varga
- 2Water content matters more than people think. If a vial is carrying residual…7 comments in this branch · started by u/marta_dziedzic