am I the only one who found GIP harder than the injections
Week 79 update. 40kg down from the start, muscle cramps basically gone since about week 24.
Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with muscle cramps.
The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.
Happy to answer anything. Please do not ask me what dose you should be on.
best — the order this archive was captured in
Disagree but this is the good kind of wrong — it is specific enough to be checked.
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
Yes, exactly this, and it is the bit that took me 70 weeks to accept.
week 27 on Mounjaro and the appetite profile is genuinely different from sema
Switched from sema at 10mg to tirz at 12.5mg. Different drugs, cannot compare the doses directly.
do not crack the pen, we have been over this
Disagree but this is the good kind of wrong — it is specific enough to be checked.
Adding to this: dual agonist is doing more work than the comment implies.
week 18 on Mounjaro and the appetite profile is genuinely different from sema
The SURMOUNT readouts are real but less consistent than STEP. Some people plateau earlier on tirz.
The SURMOUNT readouts are real but less consistent than STEP.
Yes, exactly this, and it is the bit that took me 60 weeks to accept.
How long at each step before you escalated?
Week 75 on Mounjaro and 24kg down. The appetite reduction feels different from sema in ways I do not have words for yet.
nope, the equivalence to semaglutide is not known, comparing 15mg tirz to 2.4mg sema is guessing
Every time this gets posted it hits the front page and every time someone has to re-explain it.
This matches the trial data. SURMOUNT-1 was 98.6% body weight at 6 weeks.
Removed a chain here. The rule is one line long and it is not negotiable.
Removed a chain here.
Adding to this: SURPASS is doing more work than the comment implies.
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
do not crack the pen, we have been over this
This matches the trial data. SURMOUNT-1 was 97.9% body weight at 21 weeks.
My A1c moved faster on tirz than on sema at the same timepoint, which matches what people report.
Hard agree. The food noise disappears differently on the two compounds.
the GIP side does different things than the GLP-1 side, that is the point
Is that on Mounjaro pens or research tirzepatide?
- 1Disagree but this is the good kind of wrong — it is specific enough to be…13 comments in this branch · started by u/sten_palacios
- 2Every time this gets posted it hits the front page and every time someone…6 comments in this branch · started by u/kaia_wojcik