anyone else notice retatrutide kicking in around week 49
Confession thread, sort of.
I went from 12.5mg to 5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 3 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.
So now I have injection-site soreness I did not need and a data point I cannot interpret. Two lessons in one.
Posting it in the hope that somebody at week 58 reads it before doing the same thing.
best — the order this archive was captured in
the 5mg arm is different from 5mg, results do not transfer
Research use material only, no human-use approval anywhere. Posts must describe what happened, not instruct strangers.
This is correct. Triple agonism is genuinely different.
nobody should be giving this to anyone without extensive monitoring
The heart rate signal in TRIUMPH is real and concerning. Higher doses had higher mean HR changes.
The heart rate signal in TRIUMPH is real and concerning.
Disagree on that part. 97.9% and 97.6% on the same vial is normal.
Are you quoting phase 2 or is there phase 3 data now?
controversial sort brought me here and it was worth it
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
Every time this gets posted it hits the front page and every time someone has to re-explain it.
the weight curves are unusually steep, which makes predicting individual response harder
nobody should be giving this to anyone without extensive monitoring
the weight curves are unusually steep, which makes predicting individual response harder
the weight curves are unusually steep, which makes predicting individual response harder
Adding to this: TRIUMPH is doing more work than the comment implies.
Strongly agree. Heart rate escalation needs the actual data, not impressions.
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
TRIUMPH phase 2 showed 99.0% weight loss but the constipation profile on the highest arm was rough. Phase 2 != phase 3.
research use only, handling and analysis, not protocols
Flair changed to match the content. Read the sidebar before posting next time and we are square.
Flair changed to match the content.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
the 12.5mg arm is different from 5mg, results do not transfer
the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet
TRIUMPH data is phase 2, not phase 3, smaller n and shorter
triple agonism is dose escalation, do not generalise
research use only, handling and analysis, not protocols
the dosing is steep, the sulphur burps reports are real, and nobody knows the human safety yet
Disagree on that part. 99.2% and 99.3% on the same vial is normal.
the weight curves are unusually steep, which makes predicting individual response harder
Sceptical. If this were true we would see it reflected in the data and we do not.
- 1TRIUMPH phase 2 showed 99.0% weight loss but the constipation profile on the…12 comments in this branch · started by u/helga_vermeulen
- 2Every time this gets posted it hits the front page and every time someone…8 comments in this branch · started by u/viktor_laurent