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c/orforglipron·submitted 2 years ago by u/hedda_ekstrom

ACHIEVE — my 19-week log, condensed into one table

Trial Databranch of 8 comments

ACHIEVE. That is the whole post, but I will justify it. Everything else people worry about in c/bpc157 is downstream of it. Titration speed, muscle cramps, the endless dose arguments — most of it resolves if you sort ACHIEVE out first, and almost nobody does. I say this having got it wrong for 9 months. My hs-CRP was…

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This branch

8 comments, started 2 years ago
u/nils_ferreira9 points·2 years ago

Not convinced. The evidence does not support that reading.

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u/erez_yilmaz4 points·2 years ago

the fatigue profile is speculative at this stage

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u/greta_nilsen3 points·2 years ago·edited

Stalled for 10 weeks, changed nothing, and it started moving again on week 14.

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u/first_hundred1 point·2 years ago

Stalled for 10 weeks, changed nothing, and it started moving again on week 14.

Adding to this: non-peptide is doing more work than the comment implies.

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u/trialwatch_theotrial nerd2 points·2 years ago

Yeah, small molecule changes the whole game.

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u/hazard_ratio_halstats2 points·2 years ago

small molecule, not a peptide, purity discussion is different

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u/hedda_ekstromOP1 point·2 years ago

Ireland here. Waited 3 months on a list, gave up, went private, and the total cost was roughly what I expected.

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u/meera_sandvik1 point·2 years ago

cite ATTAIN/ACHIEVE arms specifically

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The small-molecule oral: why a non-peptide agonist escapes the absorption problems of oral semaglutide, what the ATTAIN and ACHIEVE readouts showed, and what a pill with no refrigeration requirement would do to the entire supply conversation this site is built around.

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