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c/glp1women·submitted 2 months ago by u/katrin_diallo

[Results] 7 weeks, 40kg, and contraception was the hard part

Resultsbranch of 10 comments

Genuinely asking, not being difficult. Everyone in c/darkspot repeats that insulin resistance is important. I believe it, but I have never seen anyone show why, and when I search I get 13 threads of people agreeing with each other. Is there a paper? Is there a measurement? Or is this one of those things that is true…

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10 comments, started 2 months ago
u/emil_marchand-36 points·2 months ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/katrin_dialloOP1 point·2 months ago

The the food-noise thing was genuinely awful for three weeks and then simply stopped. I know that is not useful information, but it is what happened.

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u/zaid_roos1 point·2 months ago·edited

hormonal contraception interactions are speculative

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u/elin_lindqvist1 point·2 months ago

Which country? Half the answers in this thread only apply in France.

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u/ilias_kaufmann1 point·2 months ago

Strongly agree. Cycle changes are documented.

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u/jarno_karlsen1 point·2 months ago

I am going to push back on this slightly.

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u/anders_karlsen-46 points·2 months ago

Not convinced. The evidence does not support that reading.

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The questions the trials under-powered: PCOS and insulin resistance, cycle changes, fertility signal and contraception interactions, perimenopause and menopause weight physiology, and the fact that the pregnancy answer is always "not while trying, talk to your clinician".

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