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c/compounding·posted 1 year ago by u/solene_eriksen

what would you tell week-1 you about compounding

Regulatory Slow Clap ×8 Sourced ×1 Clean Column ×3

I have had 17 orders now and I keep a table, so here is the honest summary rather than a vibe.

Material has been consistent. Communication has not. Shipping has varied by about 20 days on nominally the same lane, which matters more in summer than in February.

The independent number came back 96.8% against a claimed 97.2%, which I read as agreement rather than a discrepancy — inter-lab variance on this assay is a point or two either way and treating one lab as ground truth is how people end up in pointless arguments with vendors.

Batch number is in the comments. Ask if you want the method.

3,920 up / 959 down80% upvoted57 commentsid 1noxjv19 Feb 2025

57 comments

30 in this archive, depth 5

best — the order this archive was captured in

u/kian_ferreira263 points·1 year ago

What is the actual shortage list status right now?

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u/formulary_fighterMOD145 points·1 year ago

This is an urgent-care question wearing a forum question's clothes. Please contact a clinician rather than waiting for replies.

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u/ruben_cabrera46 points·1 year ago·edited

Are we talking 503A or 503B?

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u/ayesha_radich207 points·1 year ago

What is the actual shortage list status right now?

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/honest_syringe_2025175 points·1 year ago

Crossposting this to c/maintenancephase because the people who need it are not reading this community.

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u/solene_eriksenOP92 points·1 year ago

no pharmacy referral codes, naming is fine, recruiting is not

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u/solene_eriksenOP61 points·1 year ago·edited

503B compounding is different from 503A, different rules, different legality

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u/marit_mwangi51 points·1 year ago

Yeah, 503A and 503B are different regulatory animals.

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u/chidi_demir50 points·1 year ago

Are we talking 503A or 503B?

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u/helga_vermeulen96 points·1 year ago

Rodent data is rodent data. Dose scaling is not linear and the models tell you what to investigate, not what to expect.

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u/milos_mensa39 points·1 year ago

telehealth prescriber models exist, pricing differs by state

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[deleted]43 points·1 year ago

[deleted]

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u/controversial_only53 points·1 year ago

This is correct. The shortage list does expire and the rules change.

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u/solene_eriksenOP38 points·1 year ago

Respectfully this is a sample of one presented as a finding.

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u/hugo_bergstrom103 points·1 year ago

the shortage list is temporary, it ends and compounding becomes illegal again

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u/lina_ndiaye-33 points·1 year ago

the shortage list is temporary, it ends and compounding becomes illegal again

Disagree on that part. 98.7% and 98.9% on the same vial is normal.

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u/naomi_erdogan1 point·1 year ago

Yeah, 503A and 503B are different regulatory animals.

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u/hydration_hank86 points·1 year ago

the the UK situation is different from the US, different regulations

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u/step_count_stan51 points·1 year ago

Strongly agree. API source transparency matters.

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u/sofia_nascimento28 points·1 year ago

No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.

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u/ignacio_vanhecke16 points·1 year ago

no pharmacy referral codes, naming is fine, recruiting is not

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u/lukas_delgado12 points·1 year ago

Strongly agree. API source transparency matters.

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u/medutest_mel4 points·1 year ago

the 503A/503B distinction is load-bearing, do not blur it

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u/priya_palacios3 points·1 year ago·edited

the 503A/503B distinction is load-bearing, do not blur it

Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.

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u/rina_sobczak35 points·1 year ago

telehealth prescriber models exist, pricing differs by state

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u/eu_apotheke_a19 points·1 year ago

I am going to push back on this slightly.

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u/lukas_vermeulen16 points·1 year ago

API transparency is the question that separates good compounders from sketchy ones

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u/lift_heavy_thingsresistance training12 points·1 year ago

the 503A/503B distinction is load-bearing, do not blur it

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u/ireland_drugs_pay28 points·1 year ago

the 503A/503B distinction is load-bearing, do not blur it

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u/emil_okwuosa0 points·1 year ago

You have restated the marketing copy. What is the actual substance here.

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About c/compounding

Compounded GLP-1s as a supply route: the 503A/503B distinction, the shortage-list mechanics that made compounding legal and then didn't, state board rules, telehealth prescriber models, and what a compounding pharmacy will and will not tell you about its API source.

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c/compounding rules
  1. Regulatory claims need a citation to the actual rule, notice or docket.
  2. No pharmacy referral codes. Naming a pharmacy is fine; recruiting for it is not.
  3. API source questions are on-topic and pharmacies dodging them is newsworthy.
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  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
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