c/compounding wiki

What this community is for

Compounded GLP-1s as a supply route: the 503A/503B distinction, the shortage-list mechanics that made compounding legal and then didn't, state board rules, telehealth prescriber models, and what a compounding pharmacy will and will not tell you about its API source.

c/compounding was created on 9 Oct 2023 and currently has 52,700 members and 95 captured submissions. It sits in the second tier of the site, which mostly affects how fast a question gets answered rather than how well.

Rules, and why each exists

Community rules come first, then the six site-wide rules that apply everywhere on GLP Research Hub. Community rules are enforced by the moderators listed at the bottom of this page; site rules are enforced by everyone.

1. Regulatory claims need a citation to the actual rule, notice or docket.
2. No pharmacy referral codes. Naming a pharmacy is fine; recruiting for it is not.
3. API source questions are on-topic and pharmacies dodging them is newsworthy.

And the site rules, which are short on purpose:

1. Independent community. Nobody here sells anything, and anyone who tries is banned.
2. Not medical advice. Describe what you did; never prescribe to a stranger.
3. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
4. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
5. No contact handles, wallet addresses or tracking numbers — they identify people.
6. Be recognisably decent. Disagree hard, insult nobody.

Terms you will see

Vocabulary that turns up constantly in c/compounding. Each links to the topic page, which collects every submission that touches it.

• compounding — discussed frequently in this community — see the topic page for every submission that touches it.
• 503A — discussed frequently in this community — see the topic page for every submission that touches it.
• 503B — discussed frequently in this community — see the topic page for every submission that touches it.
• shortage list — discussed frequently in this community — see the topic page for every submission that touches it.
• telehealth — discussed frequently in this community — see the topic page for every submission that touches it.
• API source — discussed frequently in this community — see the topic page for every submission that touches it.
• state board — discussed frequently in this community — see the topic page for every submission that touches it.

Start here

The twelve highest-scoring submissions in this community. Not necessarily the most correct — the most agreed-with, which is a different thing, and worth remembering when you read them.

1. [Lab] SGN survo — VendorInvestigate came back 93.7% against a claimed 98.6% — 5.3k points, 40 comments, 2 years ago
2. stalled for 7 weeks at 2.5mg and I refuse to panic this time — 5.3k points, 26 comments, 2 years ago
3. [Results] 72 weeks, 15kg, and API source was the hard part — 4.4k points, 36 comments, 1 year ago
4. week 66 check-in — 32kg down, nausea manageable, one thing confusing me — 4.4k points, 36 comments, 2 years ago
5. my TSH moved and I cannot work out whether API source is why — 4.4k points, 33 comments, 1 year ago
6. compounding — 17 things I got wrong before I got it right — 4.1k points, 40 comments, 1 year ago
7. three years of 503A threads, summarised so you do not have to read them — 4k points, 34 comments, 1 year ago
8. API source: the version I wish someone had shown me in week 1 — 3.6k points, 44 comments, 1 year ago
9. 21 months in and telehealth is still the thing I get wrong — 3.3k points, 32 comments, 2 years ago
10. [Question] Ireland — has anyone got a straight answer on API source — 3.1k points, 28 comments, 1 year ago
11. what would you tell week-1 you about compounding — 3k points, 57 comments, 1 year ago
12. help me understand 503A, I have read the wiki twice — 2.9k points, 39 comments, 2 years ago

Asked constantly

• [Question] does anyone get a COA from their compounding pharmacy
• telehealth: the version I wish someone had shown me in week 1
• [Question] 503A — what am I missing here
• why does nobody talk about shortage list
• what changed for me between week 20 and week 63
• [Question] 503B — what am I missing here
• three years of telehealth threads, summarised so you do not have to read them
• [Question] Ireland — has anyone got a straight answer on 503A
• [Question] API source — what am I missing here
• [Question] Ireland — has anyone got a straight answer on API source

If your question is on that list, read the answers there first. If it is not, ask it — that is what the community is for, and "this has been asked" is only a helpful reply when it comes with a link.

Who runs this

Moderation here is done by volunteers who also post as normal members. They are not clinicians, not vendors, and not paid.

• u/formulary_fighter — Read the formulary exclusion list before you read the marketing.
• u/usp_appendix — I read monographs for fun. Yes, that is a personality.
• u/quiet_moderator — I remove the obvious stuff so you never see it. Message the modmail, not me.
• u/prior_auth_pain — Four denials, three appeals, one external review, eventually approved. Templates in my posts.