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c/coa·posted 1 year ago by u/amylin_amy

stalled for 17 weeks at 7.5mg and I refuse to panic this time

Question Cold Box ×1 Long Haul ×2 Receipts ×3

area percent. That is the whole post, but I will justify it.

Everything else people worry about in c/darkspot is downstream of it. Titration speed, reflux, the endless dose arguments — most of it resolves if you sort area percent out first, and almost nobody does.

I say this having got it wrong for 23 months. My fasting insulin was the thing that eventually made me pay attention, which is a stupid way to learn a lesson that was in the sidebar the whole time.

3,871 up / 785 down83% upvoted41 commentsid yuxoew7 Apr 2025

41 comments

18 in this archive, depth 5

best — the order this archive was captured in

u/soren_zamora-19 points·1 year ago

chromatogram or it did not happen

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[deleted]1 point·1 year ago

[deleted]

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u/amylin_amyOPamylin1 point·1 year ago

Tested the GLB raw material and a reseller vial side-by-side. Same purity claim, different impurity profiles. Handling matters.

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u/ghrp_history1 point·1 year ago

Tested the GLB raw material and a reseller vial side-by-side.

Adding to this: area percent is doing more work than the comment implies.

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u/emeka_beaulieu1 point·1 year ago

the batch number or it did not happen

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u/amara_halonen1 point·1 year ago

redact your own name, not the vendor's batch details

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u/first_hundred1 point·1 year ago

the batch number or it did not happen

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u/meera_sandvik1 point·1 year ago

the batch number or it did not happen

Adding to this: water content is doing more work than the comment implies.

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u/ismael_eriksen375 points·1 year ago

Strongly agree. Mass% and area% are answering different questions on the same document.

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u/amylin_amyOPamylin198 points·1 year ago

Tested the GLB raw material and a reseller vial side-by-side. Same purity claim, different impurity profiles. Handling matters.

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u/laila_yilmaz290 points·1 year ago

This is the "correlation is mechanism" thing again. You changed three variables at once.

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u/foam_head_fred139 points·1 year ago

no "is this good?" without saying what the compound and claimed purity are

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u/zeynep_zielinski107 points·1 year ago

area% is not mass%, and here is exactly why it matters

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u/janek_ferrari86 points·1 year ago·edited

Yeah, 96.8% area is not the problem, the missing impurity breakdown is the problem.

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u/ignacio_silva164 points·1 year ago

the counterion is part of the mass you paid for

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u/purity_pedantMOD137 points·1 year ago

Removed a chain here. The rule is one line long and it is not negotiable.

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u/clara_restrepo199 points·1 year ago

Slight fix: the number was 97.6, not 97.4. Decimal point, but a fairly consequential one.

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u/cesar_ivaturi288 points·1 year ago

What is the method line say? Not the technique, the actual method.

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About c/coa

How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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