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c/coa·posted 1 year ago by u/valeria_karlsen

related substances — my 21-week log, condensed into one table

Lab Cold Box ×9 The Quiet One ×1 Well Actually ×2

Week 50 update. 31kg down from the start, muscle cramps basically gone since about week 90.

Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with muscle cramps.

The part that surprised me is how much of this is admin. Ordering, storing, logging, remembering. Nobody mentions that the hard bit is not the drug, it is the routine.

Happy to answer anything. Please do not ask me what dose you should be on.

51,139 up / 37,983 down57% upvoted45 commentsid 1x7tt312 Aug 2024

45 comments

23 in this archive, depth 5

best — the order this archive was captured in

u/first_hundred3.1k points·1 year ago·edited

the counterion is part of the mass you paid for

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u/valeria_karlsenOP3.7k points·1 year ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

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u/valeria_girard1.2k points·1 year ago

Disagree but this is the good kind of wrong — it is specific enough to be checked.

Adding to this: purity is doing more work than the comment implies.

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u/nikhil_lindqvist5.3k points·1 year ago

axis labels included, always

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u/sunday_shot_sal2k points·1 year ago

The COA I was holding said 96.8% area and I thought it was trash. Turns out the method was solid and the impurity profile was clean.

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u/purity_pedantMOD1k points·1 year ago

Flair changed to match the content. Read the sidebar before posting next time and we are square.

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u/laila_yilmaz693 points·1 year ago

chromatogram or it did not happen

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u/laila_yilmaz294 points·1 year ago

PDF metadata is checkable in fifteen seconds

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u/elodie_yilmaz227 points·1 year ago

Strongly agree. Mass% and area% are answering different questions on the same document.

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u/ismael_eriksen180 points·1 year ago

no "is this good?" without saying what the compound and claimed purity are

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u/foam_head_fred799 points·1 year ago

Flair changed to match the content.

Adding to this: batch is doing more work than the comment implies.

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u/reflux_report622 points·1 year ago·edited

post the whole document, not the headline number

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u/tidy_vialdrawer_watch1.1k points·1 year ago·edited

the counterion is part of the mass you paid for

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[removed]717 points·1 year ago

[removed by moderator]

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u/priya_palacios-9 points·1 year ago

Yeah, 96.8% area is not the problem, the missing impurity breakdown is the problem.

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u/sig_figs_sammod · analytical931 points·1 year ago

redact your own name, not the vendor's batch details

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u/andres_restrepo978 points·1 year ago

Cosigning. The batch number is load-bearing information.

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u/purity_pedantanalytical492 points·1 year ago

Four months on the site and I was confusing area% and mass% in every post I made. One explainer thread and it clicked.

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u/spreadsheet_gremlindata132 points·1 year ago

chromatogram or it did not happen

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u/meera_sandvik61 points·1 year ago

Not to be pedantic but COA and area percent are being used interchangeably and they are not interchangeable in real life.

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u/anders_kuusela144 points·1 year ago

Are you looking at area% or net peptide content? Different numbers.

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u/zeynep_zielinski324 points·1 year ago

The confident tone is doing a lot of work that the evidence is not.

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u/gastric_emptying_g474 points·1 year ago

no "is this good?" without saying what the compound and claimed purity are

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About c/coa

How to read a certificate of analysis and what it does and does not tell you. Area% versus mass%, identity versus quantity, water content, related substances, acetate counterions, and the difference between a vendor-supplied COA and an independent test on the vial you actually received.

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c/coa rules
  1. Post the full document. Cropped COAs that hide the batch number or date get removed.
  2. Redact your own name and order id, not the vendor's batch details.
  3. No "is this good?" without saying what the compound and claimed purity are.
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