week 61 check-in — 41kg down, nausea manageable, one thing confusing me
Confession thread, sort of.
I went from 0.5mg to 12.5mg much faster than I should have because the scale had stalled and I got impatient. The stall broke about 6 weeks later, at which point I had no way of knowing whether the dose increase did anything or whether it would have broken anyway.
So now I have reflux I did not need and a data point I cannot interpret. Two lessons in one.
Posting it in the hope that somebody at week 93 reads it before doing the same thing.
best — the order this archive was captured in
Flair changed to match the content. Read the sidebar before posting next time and we are square.
tendon and cagrilintide literature in rodents is interesting
This is correct. The co-agonism is real.
The research community is small on cagrilintide. Forum lore changes faster than data.
Yeah, amylin is doing different work than GLP-1.
tendon and CagriSema literature in rodents is interesting
not approved anywhere, keep posts descriptive, not instructional
amylin is not a GLP-1, posts conflating them get corrected
Not convinced. The evidence does not support that reading.
You have restated the marketing copy. What is the actual substance here.
You have restated the marketing copy.
Disagree on that part. 97.4% and 97.6% on the same vial is normal.
the amylin agonist pool is small, community is amylin
the amylin agonist pool is small, community is amylin
Disagree on that part. 98.7% and 98.7% on the same vial is normal.
That is net peptide content, not purity. Different number, different meaning.
the amylin agonist pool is small, community is satiety
This is correct. The co-agonism is real.
CagriSema ratios in trials are fixed, do not extrapolate self-mixing
Disagree but this is the good kind of wrong — it is specific enough to be checked.
REDEFINE readouts are phase 7 data
No. This is the kind of confident post that gets copied into a screenshot and repeated for years. Where is the evidence.
Not convinced. The evidence does not support that reading.
the co-agonism question is real and interesting
This is correct. The co-agonism is real.
long-acting amylin is satiety, different satiety profile
tendon and CagriSema literature in rodents is interesting
- 1This is correct. The co-agonism is real.10 comments in this branch · started by u/pancreatitis_scare
- 2the amylin agonist pool is small, community is amylin10 comments in this branch · started by u/tomas_kimani