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c/cagrilintide·submitted 5 months ago by u/ms_fragmenter

week 76 check-in — 22kg down, muscle cramps manageable, one thing confusing me

Cautionbranch of 9 comments

Something I noticed reading old threads that I have not seen said out loud. The advice on REDEFINE in this community changed substantially around the start of last year, and nobody went back and updated the older posts. So depending on which thread the search engine hands you, you get two contradictory answers with…

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9 comments, started 5 months ago
u/georgi_chowdhury33 points·5 months ago

The research community is small on cagrilintide. Forum lore changes faster than data.

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u/hugo_pires26 points·5 months ago·edited

Respectfully this is a sample of one presented as a finding.

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u/emeka_beaulieu10 points·5 months ago

The practical rule people converge on is 28 days at fridge temperature after first puncture, and that comes from the preservative, not the peptide.

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u/zaid_balogun0 points·5 months ago

Yeah, amylin is doing different work than GLP-1.

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u/emil_agyeman25 points·5 months ago

CagriSema ratios in trials are fixed, do not extrapolate self-mixing

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u/titration_marshalmod · c/semaglutide15 points·5 months ago

research use only, no human protocols in posts

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u/wrong_network_w4 points·5 months ago

amylin is not a GLP-1, posts conflating them get corrected

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[deleted]6 points·5 months ago

[deleted]

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u/ilias_kaufmann19 points·5 months ago

Strongly agree. REDEFINE is phase 23, not final.

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About c/cagrilintide

Amylin analog pharmacology and the CagriSema combination: why amylin and GLP-1 co-agonism produces a different satiety profile, the REDEFINE readouts, and the very limited pool of people handling cagrilintide as research material.

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