why does nobody talk about Mounjaro
Right, the Mounjaro question again, but with numbers this time.
I have 23 data points over 8 weeks. The pattern is consistent enough that I do not think it is chance, and boring enough that nobody is going to screenshot it, which is usually a good sign.
The thing I would flag for anyone new: the effect I am describing showed up at week 24, not week 73. People give up long before the interesting part.
Interested in whether this matches other people's logs or whether I am an outlier.
best — the order this archive was captured in
Titration speed is a side-effect dial far more than an efficacy dial.
the 15mg is the top of the pen, not the required dose
The SURMOUNT readouts are real but less consistent than STEP. Some people plateau earlier on tirz.
How long at each step before you escalated?
the appetite change on tirz is more than just reduced hunger, it is different machinery
How long at each step before you escalated?
Disagree on that part. 98.7% and 98.1% on the same vial is normal.
the early fullness from tirz is different, not necessarily worse
do not crack the pen, we have been over this
You have restated the marketing copy. What is the actual substance here.
Edit to your parent would help — the concentration you quoted assumes one scenario and you have written another above it.
This matches the trial data. SURMOUNT-1 was 99.2% body weight at 20 weeks.
the 15mg is the top of the pen, not the required dose
dual agonism is Mounjaro, do not generalise from semaglutide
the appetite change on tirz is more than just reduced hunger, it is different machinery
Sceptical. If this were true we would see it reflected in the data and we do not.
the appetite change on tirz is more than just reduced hunger, it is different machinery
This matches the trial data. SURMOUNT-1 was 97.9% body weight at 11 weeks.
This matches the trial data.
Counter-anecdote: opposite result, same dose. Which mostly tells us the variance is huge.
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SURMOUNT data is messier than STEP data but the weight loss is there
the GIP side does different things than the GLP-1 side, that is the point
SURMOUNT data is messier than STEP data but the weight loss is there
Yes, exactly this, and it is the bit that took me 84 weeks to accept.
Did you stay on semaglutide or switch? The outcome is different if you are comparing.
the appetite change on tirz is more than just reduced hunger, it is different machinery
the appetite change on tirz is more than just reduced hunger, it is different machinery
Disagree on that part. 97.6% and 97.9% on the same vial is normal.
Did you stay on semaglutide or switch?
Adding to this: dual agonist is doing more work than the comment implies.
Yeah, dual agonism does produce a different appetite profile than GLP-1 alone.
The SURMOUNT readouts are real but less consistent than STEP. Some people plateau earlier on tirz.
- 1i have this exact spreadsheet16 comments in this branch · started by u/kaia_cabrera
- 2How long at each step before you escalated?4 comments in this branch · started by u/rania_marchand