GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Single comment threadYou are looking at one branch of small win: GIP stopped being a problem at week 31 — 28 comments in the full submission. View in context.
540
c/tirzepatide·submitted 1 months ago by u/copay_card_cc

small win: GIP stopped being a problem at week 31

Questionbranch of 5 comments

Week 45 update. 46kg down from the start, early fullness basically gone since about week 85. Things that worked: consistency, protein at breakfast, walking more than I want to. Things that did not: everything I bought on the internet to help with early fullness. The part that surprised me is how much of this is…

Read the full submission and all 28 comments →

This branch

5 comments, started 1 months ago
u/emil_barros51 points·1 months ago

The dual agonism story is real. The appetite is physically different from semaglutide alone.

replysharereportpermalink
u/georgi_chowdhury18 points·1 months ago

do not crack the pen, we have been over this

replysharereportpermalink
u/tidy_vialdrawer_pls6 points·1 months ago

do not crack the pen, we have been over this

Adding to this: dual agonist is doing more work than the comment implies.

replysharereportpermalink
u/tarek_kirchner60 points·1 months ago

Strongly agree. Tirz is better than sema is not a claim without a comparator dose.

replysharereportpermalink
u/adnan_nascimento25 points·1 months ago

Hard agree. The food noise disappears differently on the two compounds.

replysharereportpermalink

← back to the whole thread

About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

187kmembers
130submissions
Aug 2023created
submissions / month, last year
Sponsored

Sigma-Aldrich Standards

Certified reference materials for peptide identity and purity work.

sigmaaldrich.com
More in c/tirzepatide
c/tirzepatide rules
  1. "Tirz is better than sema" needs a comparator dose or it is a vibe, not a claim.
  2. Vial-splitting and self-compounding discussion stays in c/reconstitution.
  3. No pen-cracking tutorials. Discussing that people do it is fine; instructions are not.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/titration_marshalu/incretin_ivyu/quiet_moderatoru/dexa_twice_yearly
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →