GLPHubglpresearchhub.com
Read-only archive. GLP Research Hub is a static community record — nothing here is for sale, no account is needed, and no vote you cast is counted. Why?
Archived. This submission is more than a year old. Votes and new comments are closed, and some of the advice in it may have been superseded — check the community wiki for the current version.
3.4k
c/tirzepatide·posted 2 years ago by u/teodor_szabo

[Discussion] the SURMOUNT advice in here is 17 years out of date

Discussion Well Actually ×2 Slow Clap ×3 Cold Box ×1

Trying to settle this properly because the thread from last year went in circles.

The claim: SURMOUNT matters. The counter-claim: it is measurement error. Both sides have been asserting it confidently for about 19 months without either producing anything.

What would actually settle it is 17 people measuring the same thing the same way. I have started; my numbers are below. They lean one way but not strongly enough for me to declare victory.

If you have data, post the data. If you have an opinion, flair it as an opinion.

24,795 up / 21,367 down54% upvoted35 commentsid 14aajj22 Feb 2024

35 comments

8 in this archive, depth 4

best — the order this archive was captured in

u/dario_stanescu449 points·2 years ago·edited

the GIP side does different things than the GLP-1 side, that is the point

replysharereportpermalink
u/thyroid_tangent-10 points·2 years ago

You have restated the marketing copy. What is the actual substance here.

replysharereportpermalink
u/copay_card_cc1 point·2 years ago

week 22 on Mounjaro and the appetite profile is genuinely different from sema

replysharereportpermalink
u/marta_dziedzic1 point·2 years ago

Is that on Mounjaro pens or research tirzepatide?

replysharereportpermalink
u/nordic_pricing1 point·2 years ago

stalled on sema, tried tirz, and the curves were actually different shapes

replysharereportpermalink
[removed]1 point·2 years ago

[removed by moderator]

replysharereportpermalink
u/thyroid_tangent1 point·2 years ago

You have restated the marketing copy. What is the actual substance here.

replysharereportpermalink
u/gentle_correctionnice about it463 points·2 years ago·edited
tl;dr for anyone scrolling: SURPASS
replysharereportpermalink
Permalinked branches
Deep branches get their own page so a single reply chain can be linked and read on its own.
About c/tirzepatide

Tirzepatide-specific discussion: the dual-agonist pharmacology, the 2.5 → 15mg ladder, the appetite profile people describe as different from semaglutide, and the SURMOUNT/SURPASS trial programme. Comparisons with semaglutide are welcome as long as they are specific about dose equivalence being unknown.

187kmembers
130submissions
Aug 2023created
submissions / month, last year
Sponsored

PeptideMeter Analytics

Independent testing plus vendor-level trend data. Community-funded, unaffiliated.

peptidemeter.com
More in c/tirzepatide
c/tirzepatide rules
  1. "Tirz is better than sema" needs a comparator dose or it is a vibe, not a claim.
  2. Vial-splitting and self-compounding discussion stays in c/reconstitution.
  3. No pen-cracking tutorials. Discussing that people do it is fine; instructions are not.
  4. Independent community. Nobody here sells anything, and anyone who tries is banned.
  5. Not medical advice. Describe what you did; never prescribe to a stranger.
  6. Claims need evidence. Batch numbers, dated screenshots, independent test reports, or a citation.
  7. No referral links, discount codes or affiliate URLs. Permanent ban, no appeal.
  8. No contact handles, wallet addresses or tracking numbers — they identify people.
  9. Be recognisably decent. Disagree hard, insult nobody.
Full rules and how they are enforced →
Moderators
u/titration_marshalu/incretin_ivyu/quiet_moderatoru/dexa_twice_yearly
Volunteers. Unpaid, unaffiliated, and reachable through modmail only.
Before you read on

Several compounds discussed on GLP Research Hub are sold for research use only and are not approved for human use anywhere. Nothing here is medical advice and none of it is written by your clinician. If a post reads like an instruction, treat it as a description of what one stranger did.

Full disclaimer →